Adverse Drug Reaction Classification System

ADR Ontology
ADR Term Papillitis
ADR ID BADD_A03284
ADR Hierarchy
08      General disorders and administration site conditions
08.01      General system disorders NEC
08.01.05      Inflammations
08.01.05.002      Papillitis
Description Swelling of the OPTIC DISK, usually in association with increased intracranial pressure, characterized by hyperemia, blurring of the disk margins, microhemorrhages, blind spot enlargement, and engorgement of retinal veins. Chronic papilledema may cause OPTIC ATROPHY and visual loss. (Miller et al., Clinical Neuro-Ophthalmology, 4th ed, p175) [MeSH]
MedDRA Code 10033708
MeSH ID D010211
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE) Not Available
Synonym
Papillitis | Papillitis NOS | Papilledema | Optic Disk Edema | Edema, Optic Disk | Edemas, Optic Disk | Optic Nerve Papillitis | Papillitis, Optic Nerve | Papillitis, Optic | Optic Papillitis | Choked Disk | Choked Disks | Disk, Choked | Disks, Choked | Optic Papilla Edema | Edema, Optic Papilla | Papilledema Associated with Increased Intracranial Pressure | Increased Intracranial Pressure-Associated Papilledema | Increased Intracranial Pressure Associated Papilledema | Edema of the optic disc | Retinal Edema | Edema, Retinal | Edemas, Retinal | Retinal Edemas | Decreased Intraocular Pressure-Associated Papilledema | Decreased Intraocular Pressure Associated Papilledema | Papilledema Associated with Decreased Intraocular Pressure
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D01119Ibrutinib0.000112%
BADD_D01275Levofloxacin0.000084%
BADD_D01285Levothyroxine0.000005%
BADD_D01401Metformin0.000008%
BADD_D01533Naproxen--
BADD_D01534Naproxen sodium--
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