Adverse Drug Reaction Classification System

         

ADR Ontology
ADR Term Paraplegia
ADR ID BADD_A03300
ADR Hierarchy
17      Nervous system disorders
17.01      Movement disorders (incl parkinsonism)
17.01.04      Paralysis and paresis (excl cranial nerve)
17.01.04.007      Paraplegia
Description Severe or complete loss of motor function in the lower extremities and lower portions of the trunk. This condition is most often associated with SPINAL CORD DISEASES, although BRAIN DISEASES; PERIPHERAL NERVOUS SYSTEM DISEASES; NEUROMUSCULAR DISEASES; and MUSCULAR DISEASES may also cause bilateral leg weakness. [MeSH]
MedDRA Code 10033892
MeSH ID D010264
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE) Not Available
Synonym
Acute paraplegia | Paraplegia | Paraplegic | Spastic paraplegia | Paraplegias | Paralysis, Legs | Paralysis, Lower Limbs | Paralysis, Lower Extremities | Paraplegia, Spinal | Paraplegias, Spinal | Spinal Paraplegia | Spinal Paraplegias | Paraplegia, Flaccid | Flaccid Paraplegia | Flaccid Paraplegias | Paraplegias, Flaccid | Paraplegia, Spastic | Paraplegias, Spastic | Spastic Paraplegias | Spastic Paraplegia | Paraplegia, Ataxic | Ataxic Paraplegia | Ataxic Paraplegias | Paraplegias, Ataxic | Paraplegia, Cerebral | Cerebral Paraplegia | Cerebral Paraplegias | Paraplegias, Cerebral
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00014Abiraterone0.000501%
BADD_D00033Acetylsalicylic acid0.000022%
BADD_D00066Alendronic acid0.000044%
BADD_D00130Amphetamine0.000080%
BADD_D00151Apixaban0.000217%
BADD_D00209Baclofen0.000174%
BADD_D00260Betamethasone--
BADD_D00308Bupivacaine0.000357%
BADD_D00504Clopidogrel0.000064%
BADD_D00560Cytarabine0.000280%
BADD_D00561Cytarabine hydrochloride--
BADD_D00563Dabigatran0.000734%
BADD_D00623Dexamethasone0.000145%
BADD_D00680Dimethyl fumarate0.001680%
BADD_D00723Doxorubicin0.000112%
BADD_D00734Duloxetine0.000027%
BADD_D00798Eribulin0.000112%
BADD_D00974Fragmin--
BADD_D01020Glatiramer--
BADD_D01021Glatiramer acetate--
BADD_D01023Glimepiride0.000042%
BADD_D01086Hydrocortisone--
BADD_D01091Hydrocortisone sodium succinate--
BADD_D01119Ibrutinib0.000112%
BADD_D01136Imatinib0.000168%
BADD_D01186Ioversol--
BADD_D01217Itraconazole0.008017%
BADD_D01269Levobupivacaine--
BADD_D01401Metformin0.000005%
BADD_D01418Methotrexate0.000227%
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