Adverse Drug Reaction Classification System

ADR Ontology
ADR Term Patent ductus arteriosus
ADR ID BADD_A03321
ADR Hierarchy
02      Cardiac disorders
02.08      Congenital cardiac disorders
02.08.01      Congenital cardiac structural defects NEC
02.08.01.001      Patent ductus arteriosus
03      Congenital, familial and genetic disorders
03.07      Cardiac and vascular disorders congenital
03.07.01      Persistent foetal circulation disorders
03.07.01.001      Patent ductus arteriosus
24      Vascular disorders
24.03      Vascular disorders NEC
24.03.03      Vascular malformations and acquired anomalies
24.03.03.002      Patent ductus arteriosus
Description A congenital heart defect characterized by the persistent opening of fetal DUCTUS ARTERIOSUS that connects the PULMONARY ARTERY to the descending aorta (AORTA, DESCENDING) allowing unoxygenated blood to bypass the lung and flow to the PLACENTA. Normally, the ductus is closed shortly after birth. [MeSH]
MedDRA Code 10034130
MeSH ID D004374
ADR Severity Grade (FAERS) Not Available
ADR Severity Grade (CTCAE) Not Available
Synonym
Ductus arteriosus patent | Patent ductus arteriosis | Patent ductus arteriosus | PDA | Ductus Arteriosus, Patent | Patent Ductus Arteriosus | Patency of the Ductus Arteriosus | Patent Ductus Arteriosus Familial
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00342Calfactant--
BADD_D00354Captopril--
BADD_D00497Clomiphene--
BADD_D00498Clomiphene citrate--
BADD_D00967Fosinopril--
BADD_D00979Furosemide--
BADD_D01467Milrinone--
BADD_D01801Poractant alfa--
BADD_D01852Progesterone--
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