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ADR Term
ADReCS ID
MedDRA Code
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ADR Ontology
ADR Term
Personality change
ADR ID
BADD_A03390
ADR Hierarchy
17
Nervous system disorders
17.02
Neurological disorders NEC
17.02.05
Neurological signs and symptoms NEC
17.02.05.019
Personality change
19
Psychiatric disorders
19.05
Personality disorders and disturbances in behaviour
19.05.01
Behaviour and socialisation disturbances
19.05.01.006
Personality change
Description
A disorder characterized by a conspicuous change in a person's behavior and thinking. [CTCAE]
MedDRA Code
10034719
MeSH ID
Not Available
ADR Severity Grade (FAERS)
Not Available
ADR Severity Grade (CTCAE)
Synonym
Attitude change | Attitude changed | Character change | Character change in | Cognitive or personality change of other type | Personality change
Drugs Leading to the ADR
Drug ID
Drug Name
ADR Frequency (FAERS)
ADR Severity Grade (FAERS)
BADD_D00706
Donepezil
0.000070%
BADD_D00732
Droxidopa
0.000516%
BADD_D00734
Duloxetine
0.000229%
BADD_D00765
Empagliflozin
0.000355%
BADD_D00775
Enzalutamide
0.000667%
BADD_D00809
Escitalopram
0.000038%
BADD_D00870
Febuxostat
-
-
BADD_D00877
Fenoprofen
-
-
BADD_D00878
Fenoprofen calcium
-
-
BADD_D00898
Finasteride
0.000135%
BADD_D00932
Fluoxetine
0.000146%
BADD_D00947
Fluticasone propionate
-
-
BADD_D00981
Gabapentin
0.000230%
BADD_D01086
Hydrocortisone
-
-
BADD_D01091
Hydrocortisone sodium succinate
-
-
BADD_D01096
Hydromorphone
-
-
BADD_D01159
Insulin (human)
-
-
BADD_D01197
Iron
-
-
BADD_D01213
Isotretinoin
0.002804%
BADD_D01243
Lamotrigine
0.000177%
BADD_D01265
Levetiracetam
0.001805%
BADD_D01275
Levofloxacin
0.000042%
BADD_D01281
Levonorgestrel
-
-
BADD_D01285
Levothyroxine
0.000017%
BADD_D01366
Medroxyprogesterone acetate
-
-
BADD_D01397
Mesalamine
0.000183%
BADD_D01431
Methylphenidate
0.000534%
BADD_D01433
Methylprednisolone
-
-
BADD_D01434
Methylprednisolone acetate
-
-
BADD_D01435
Methylprednisolone hemisuccinate
-
-
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