Adverse Drug Reaction Classification System

         

ADR Ontology
ADR Term Plasma cell leukaemia
ADR ID BADD_A03439
ADR Hierarchy
01      Blood and lymphatic system disorders
01.14      Plasma cell neoplasms
01.14.02      Plasma cell myelomas
01.14.02.003      Plasma cell leukaemia
16      Neoplasms benign, malignant and unspecified (incl cysts and polyps)
16.23      Plasma cell neoplasms
16.23.02      Plasma cell myelomas
16.23.02.003      Plasma cell leukaemia
Description A rare, aggressive variant of MULTIPLE MYELOMA characterized by the circulation of excessive PLASMA CELLS in the peripheral blood. It can be a primary manifestation of multiple myeloma or develop as a terminal complication during the disease. [MeSH]
MedDRA Code 10035222
MeSH ID D007952
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE) Not Available
Synonym
Leukaemia plasmacytic | Leukemia plasmacytic | Plasma cell leukaemia | Plasma cell leukemia | Plasma cell leukemia without mention of remission | Plasma cell leukaemia without mention of remission | Leukemia, Plasma Cell | Leukemias, Plasma Cell | Plasma Cell Leukemias | Plasma Cell Leukemia | Plasmacytic Leukemia | Leukemia, Plasmacytic | Leukemias, Plasmacytic | Plasmacytic Leukemias
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00284Bortezomib0.000224%
BADD_D00367Carfilzomib0.000392%
BADD_D01223Ixazomib0.000168%
BADD_D01253Lenalidomide0.006896%
BADD_D01798Pomalidomide0.001567%
BADD_D02192Thalidomide0.000723%
BADD_D02345Venetoclax0.000112%
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