Adverse Drug Reaction Classification System

ADR Ontology
ADR Term Pleural effusion
ADR ID BADD_A03461
ADR Hierarchy
22      Respiratory, thoracic and mediastinal disorders
22.05      Pleural disorders
22.05.02      Pneumothorax and pleural effusions NEC
22.05.02.002      Pleural effusion
Description A disorder characterized by an increase in amounts of fluid within the pleural cavity. Symptoms include shortness of breath, cough and marked chest discomfort. [CTCAE] Presence of fluid in the pleural cavity resulting from excessive transudation or exudation from the pleural surfaces. It is a sign of disease and not a diagnosis in itself. [MeSH]
MedDRA Code 10035598
MeSH ID D010996
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE)
Synonym
Effusion pleural | Intrapleural fluid retention of | Other specified forms of pleural effusion, except tuberculous | Pleural effusion | Unspecified pleural effusion | Pleural fluid exudate | Pulmonary effusion | Pleural effusion recurrent | Trapped lung | Bilateral pleural effusion | Unilateral pleural effusion | Pleural Effusion | Effusion, Pleural | Effusions, Pleural | Pleural Effusions
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00013Abciximab--
BADD_D00014Abiraterone0.006073%
BADD_D00023Acetaminophen--
BADD_D00041Adalimumab--
BADD_D00047Afatinib0.003190%
BADD_D00066Alendronic acid0.000418%
BADD_D00100Ambrisentan--
BADD_D00115Amiodarone0.001751%
BADD_D00121Amlodipine0.000038%
BADD_D00132Amphotericin b--
BADD_D00139Anagrelide--
BADD_D00143Anidulafungin--
BADD_D00151Apixaban--
BADD_D00158Aprotinin (bovine)--
BADD_D00161Argatroban--
BADD_D00168Arsenic--
BADD_D00169Arsenic trioxide0.000224%
BADD_D00190Atropine sulfate--
BADD_D00193Axitinib0.001668%
BADD_D00194Azacitidine0.002574%
BADD_D00195Azathioprine0.001880%
BADD_D00203Azithromycin--
BADD_D00210Balsalazide--
BADD_D00211Balsalazide disodium--
BADD_D00230Bendamustine0.001254%
BADD_D00269Bexarotene0.000112%
BADD_D00271Bicalutamide0.002812%
BADD_D00277Bisoprolol0.002826%
BADD_D00279Bivalirudin--
BADD_D00284Bortezomib0.000918%
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