Adverse Drug Reaction Classification System

         

ADR Ontology
ADR Term Pleural effusion
ADR ID BADD_A03461
ADR Hierarchy
22      Respiratory, thoracic and mediastinal disorders
22.05      Pleural disorders
22.05.02      Pneumothorax and pleural effusions NEC
22.05.02.002      Pleural effusion
Description A disorder characterized by an increase in amounts of fluid within the pleural cavity. Symptoms include shortness of breath, cough and marked chest discomfort. [CTCAE] Presence of fluid in the pleural cavity resulting from excessive transudation or exudation from the pleural surfaces. It is a sign of disease and not a diagnosis in itself. [MeSH]
MedDRA Code 10035598
MeSH ID D010996
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE)
Synonym
Effusion pleural | Intrapleural fluid retention of | Other specified forms of pleural effusion, except tuberculous | Pleural effusion | Unspecified pleural effusion | Pleural fluid exudate | Pulmonary effusion | Pleural effusion recurrent | Trapped lung | Bilateral pleural effusion | Unilateral pleural effusion | Pleural Effusion | Effusion, Pleural | Effusions, Pleural | Pleural Effusions
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D02348Verapamil0.000099%
BADD_D02360Vincristine0.000168%
BADD_D02363Vinorelbine0.000112%
BADD_D02369Voriconazole--
BADD_D02373Warfarin--
BADD_D02375Water--
BADD_D02379Zaleplon--
BADD_D02392Zoledronic acid--
BADD_D02412Octreotide0.000373%
BADD_D02423Fondaparinux0.004934%
BADD_D02428Loperamide0.000338%
BADD_D02460Ganirelix0.000838%
BADD_D02467Naloxegol0.000878%
BADD_D02469Edoxaban0.000082%
BADD_D02470Nintedanib--
BADD_D02473Sodium chloride0.000603%
BADD_D02480Alectinib0.001533%
BADD_D02482Acalabrutinib0.000582%
BADD_D02483Ribociclib0.001343%
BADD_D02493Selinexor0.000112%
BADD_D02498Abemaciclib0.000582%
BADD_D02500Alpelisib0.000448%
BADD_D02503Telotristat ethyl-
BADD_D02504Lorlatinib0.001589%
BADD_D02505Gilteritinib0.000336%
BADD_D02508Edaravone0.000808%
BADD_D02509Brigatinib0.000560%
BADD_D02510Rucaparib0.001220%
BADD_D02517Enasidenib0.000224%
BADD_D02521Sodium zirconium cyclosilicate0.002478%
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