Adverse Drug Reaction Classification System

         

ADR Ontology
ADR Term Pleural effusion
ADR ID BADD_A03461
ADR Hierarchy
22      Respiratory, thoracic and mediastinal disorders
22.05      Pleural disorders
22.05.02      Pneumothorax and pleural effusions NEC
22.05.02.002      Pleural effusion
Description A disorder characterized by an increase in amounts of fluid within the pleural cavity. Symptoms include shortness of breath, cough and marked chest discomfort. [CTCAE] Presence of fluid in the pleural cavity resulting from excessive transudation or exudation from the pleural surfaces. It is a sign of disease and not a diagnosis in itself. [MeSH]
MedDRA Code 10035598
MeSH ID D010996
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE)
Synonym
Effusion pleural | Intrapleural fluid retention of | Other specified forms of pleural effusion, except tuberculous | Pleural effusion | Unspecified pleural effusion | Pleural fluid exudate | Pulmonary effusion | Pleural effusion recurrent | Trapped lung | Bilateral pleural effusion | Unilateral pleural effusion | Pleural Effusion | Effusion, Pleural | Effusions, Pleural | Pleural Effusions
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00285Bosentan0.002226%
BADD_D00286Bosutinib0.008383%
BADD_D00287Bosutinib monohydrate--
BADD_D00304Bromocriptine0.001319%
BADD_D00305Bromocriptine mesylate--
BADD_D00318Busulfan0.000112%
BADD_D00329Cabergoline0.009609%
BADD_D00330Cabozantinib0.004153%
BADD_D00349Capecitabine--
BADD_D00356Carbamazepine0.001488%
BADD_D00364Carboplatin0.002418%
BADD_D00367Carfilzomib0.001086%
BADD_D00376Caspofungin0.000224%
BADD_D00377Caspofungin acetate--
BADD_D00395Cefpodoxime--
BADD_D00405Ceftriaxone0.033424%
BADD_D00407Cefuroxime--
BADD_D00410Celecoxib--
BADD_D00412Cephalexin0.000038%
BADD_D00414Ceritinib0.000560%
BADD_D00424Cevimeline--
BADD_D00425Cevimeline hydrochloride--
BADD_D00429Chlorambucil0.000112%
BADD_D00440Chloroquine0.000213%
BADD_D00448Chlorthalidone0.000151%
BADD_D00460Ciclesonide0.000379%
BADD_D00471Ciprofloxacin--
BADD_D00474Cisplatin0.001511%
BADD_D00479Cladribine0.000306%
BADD_D00495Clofarabine--
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