Adverse Drug Reaction Classification System

         

ADR Ontology
ADR Term Pleural effusion
ADR ID BADD_A03461
ADR Hierarchy
22      Respiratory, thoracic and mediastinal disorders
22.05      Pleural disorders
22.05.02      Pneumothorax and pleural effusions NEC
22.05.02.002      Pleural effusion
Description A disorder characterized by an increase in amounts of fluid within the pleural cavity. Symptoms include shortness of breath, cough and marked chest discomfort. [CTCAE] Presence of fluid in the pleural cavity resulting from excessive transudation or exudation from the pleural surfaces. It is a sign of disease and not a diagnosis in itself. [MeSH]
MedDRA Code 10035598
MeSH ID D010996
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE)
Synonym
Effusion pleural | Intrapleural fluid retention of | Other specified forms of pleural effusion, except tuberculous | Pleural effusion | Unspecified pleural effusion | Pleural fluid exudate | Pulmonary effusion | Pleural effusion recurrent | Trapped lung | Bilateral pleural effusion | Unilateral pleural effusion | Pleural Effusion | Effusion, Pleural | Effusions, Pleural | Pleural Effusions
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D01119Ibrutinib0.010532%
BADD_D01120Ibuprofen0.000013%
BADD_D01130Idelalisib0.000336%
BADD_D01133Ifosfamide--
BADD_D01135Iloprost0.000288%
BADD_D01136Imatinib0.006212%
BADD_D01137Imatinib mesylate--
BADD_D01142Imiquimod0.000658%
BADD_D01159Insulin (human)--
BADD_D01167Interferon alfa-2b--
BADD_D01182Iopromide--
BADD_D01204Isoniazid0.008339%
BADD_D01217Itraconazole0.045429%
BADD_D01236Labetalol0.000163%
BADD_D01243Lamotrigine0.000977%
BADD_D01245Lansoprazole0.000945%
BADD_D01247Lanthanum carbonate0.001239%
BADD_D01248Lapatinib0.000224%
BADD_D01252Leflunomide--
BADD_D01253Lenalidomide--
BADD_D01254Lenvatinib0.002753%
BADD_D01257Letrozole0.003951%
BADD_D01258Leucovorin0.005576%
BADD_D01260Leuprolide acetate--
BADD_D01261Leuprolide monoacetate--
BADD_D01275Levofloxacin--
BADD_D01295Linezolid0.012349%
BADD_D01300Lisinopril--
BADD_D01301Lisuride--
BADD_D01322Losartan0.000045%
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