Adverse Drug Reaction Classification System

         

ADR Ontology
ADR Term Pleural effusion
ADR ID BADD_A03461
ADR Hierarchy
22      Respiratory, thoracic and mediastinal disorders
22.05      Pleural disorders
22.05.02      Pneumothorax and pleural effusions NEC
22.05.02.002      Pleural effusion
Description A disorder characterized by an increase in amounts of fluid within the pleural cavity. Symptoms include shortness of breath, cough and marked chest discomfort. [CTCAE] Presence of fluid in the pleural cavity resulting from excessive transudation or exudation from the pleural surfaces. It is a sign of disease and not a diagnosis in itself. [MeSH]
MedDRA Code 10035598
MeSH ID D010996
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE)
Synonym
Effusion pleural | Intrapleural fluid retention of | Other specified forms of pleural effusion, except tuberculous | Pleural effusion | Unspecified pleural effusion | Pleural fluid exudate | Pulmonary effusion | Pleural effusion recurrent | Trapped lung | Bilateral pleural effusion | Unilateral pleural effusion | Pleural Effusion | Effusion, Pleural | Effusions, Pleural | Pleural Effusions
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D01328Lubiprostone0.000426%
BADD_D01336Macitentan0.004441%
BADD_D01376Melphalan0.000224%
BADD_D01378Memantine0.000725%
BADD_D01381Mepact--
BADD_D01393Meropenem--
BADD_D01394Merrem i.v.--
BADD_D01397Mesalamine0.001683%
BADD_D01414Methimazole0.001820%
BADD_D01418Methotrexate--
BADD_D01439Methysergide--
BADD_D01470Minocycline0.000649%
BADD_D01473Minoxidil0.003858%
BADD_D01478Mitomycin0.000280%
BADD_D01479Mitotane0.000112%
BADD_D01494Monoethanolamine--
BADD_D01501Moxifloxacin--
BADD_D01502Moxifloxacin hydrochloride--
BADD_D01507Mycophenolate mofetil--
BADD_D01508Mycophenolic acid--
BADD_D01511Nabumetone0.000173%
BADD_D01513Nafarelin0.000279%
BADD_D01549Nelarabine--
BADD_D01566Nifedipine0.000149%
BADD_D01567Nilotinib0.011898%
BADD_D01570Nisoldipine--
BADD_D01574Nitric oxide-
BADD_D01576Nitrofurantoin--
BADD_D01581Nivolumab--
BADD_D01592Obeticholic acid0.003127%
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