Adverse Drug Reaction Classification System

         

ADR Ontology
ADR Term Pleural effusion
ADR ID BADD_A03461
ADR Hierarchy
22      Respiratory, thoracic and mediastinal disorders
22.05      Pleural disorders
22.05.02      Pneumothorax and pleural effusions NEC
22.05.02.002      Pleural effusion
Description A disorder characterized by an increase in amounts of fluid within the pleural cavity. Symptoms include shortness of breath, cough and marked chest discomfort. [CTCAE] Presence of fluid in the pleural cavity resulting from excessive transudation or exudation from the pleural surfaces. It is a sign of disease and not a diagnosis in itself. [MeSH]
MedDRA Code 10035598
MeSH ID D010996
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE)
Synonym
Effusion pleural | Intrapleural fluid retention of | Other specified forms of pleural effusion, except tuberculous | Pleural effusion | Unspecified pleural effusion | Pleural fluid exudate | Pulmonary effusion | Pleural effusion recurrent | Trapped lung | Bilateral pleural effusion | Unilateral pleural effusion | Pleural Effusion | Effusion, Pleural | Effusions, Pleural | Pleural Effusions
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D01834Prednisone0.000152%
BADD_D01835Pregabalin--
BADD_D01842Procainamide--
BADD_D01843Procainamide hydrochloride--
BADD_D01846Procarbazine--
BADD_D01847Procarbazine hydrochloride--
BADD_D01852Progesterone0.000376%
BADD_D01856Propafenone--
BADD_D01869Propylthiouracil0.014106%
BADD_D01916Rasagiline mesylate--
BADD_D01922Regorafenib0.001343%
BADD_D01923Remifentanil hydrochloride--
BADD_D01933Ribavirin--
BADD_D01937Rifapentine--
BADD_D01942Riluzole--
BADD_D01954Rivaroxaban--
BADD_D01955Rivastigmine0.001897%
BADD_D01956Rivastigmine tartrate--
BADD_D01961Rofecoxib--
BADD_D01964Romidepsin0.000112%
BADD_D01968Ropivacaine hydrochloride--
BADD_D01970Rosiglitazone maleate--
BADD_D01973Rotigotine0.000734%
BADD_D01978Ruxolitinib--
BADD_D02002Selegiline--
BADD_D02006Selexipag0.000370%
BADD_D02028Sirolimus0.000335%
BADD_D02029Sitagliptin0.000647%
BADD_D02031Sitaxentan--
BADD_D02058Sorafenib0.001791%
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