Adverse Drug Reaction Classification System

ADR Ontology
ADR Term Pleural effusion
ADR ID BADD_A03461
ADR Hierarchy
22      Respiratory, thoracic and mediastinal disorders
22.05      Pleural disorders
22.05.02      Pneumothorax and pleural effusions NEC
22.05.02.002      Pleural effusion
Description A disorder characterized by an increase in amounts of fluid within the pleural cavity. Symptoms include shortness of breath, cough and marked chest discomfort. [CTCAE] Presence of fluid in the pleural cavity resulting from excessive transudation or exudation from the pleural surfaces. It is a sign of disease and not a diagnosis in itself. [MeSH]
MedDRA Code 10035598
MeSH ID D010996
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE)
Synonym
Effusion pleural | Intrapleural fluid retention of | Other specified forms of pleural effusion, except tuberculous | Pleural effusion | Unspecified pleural effusion | Pleural fluid exudate | Pulmonary effusion | Pleural effusion recurrent | Trapped lung | Bilateral pleural effusion | Unilateral pleural effusion | Pleural Effusion | Effusion, Pleural | Effusions, Pleural | Pleural Effusions
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D02060Sotalol0.000422%
BADD_D02093Sulfasalazine0.001970%
BADD_D02097Sulindac--
BADD_D02100Sunitinib0.008876%
BADD_D02105Tacrolimus0.005347%
BADD_D02106Tadalafil0.001542%
BADD_D02107Tafamidis0.005653%
BADD_D02147Telmisartan0.000390%
BADD_D02151Temsirolimus--
BADD_D02160Terbinafine0.000447%
BADD_D02174Testosterone undecanoate-
BADD_D02192Thalidomide--
BADD_D02217Tigecycline--
BADD_D02232Tobramycin--
BADD_D02246Tolvaptan0.000204%
BADD_D02248Topotecan0.000112%
BADD_D02249Topotecan hydrochloride--
BADD_D02252Tositumomab--
BADD_D02253Trabectedin0.000224%
BADD_D02257Trametinib0.000694%
BADD_D02268Treprostinil0.001678%
BADD_D02270Tretinoin0.000267%
BADD_D02321Ursodiol--
BADD_D02325Valdecoxib--
BADD_D02326Valganciclovir--
BADD_D02327Valganciclovir hydrochloride--
BADD_D02329Valproic acid0.001647%
BADD_D02331Valsartan0.000291%
BADD_D02344Vemurafenib0.000728%
BADD_D02345Venetoclax0.001063%
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