Adverse Drug Reaction Classification System

         

ADR Ontology
ADR Term Polyarteritis nodosa
ADR ID BADD_A03491
ADR Hierarchy
10      Immune system disorders
10.02      Immune disorders NEC
10.02.02      Vasculitides
10.02.02.001      Polyarteritis nodosa
15      Musculoskeletal and connective tissue disorders
15.06      Connective tissue disorders (excl congenital)
15.06.01      Connective tissue disorders NEC
15.06.01.003      Polyarteritis nodosa
20      Renal and urinary disorders
20.01      Renal disorders (excl nephropathies)
20.01.02      Renal disorders NEC
20.01.02.004      Polyarteritis nodosa
24      Vascular disorders
24.12      Vascular infections and inflammations
24.12.04      Vasculitides NEC
24.12.04.019      Polyarteritis nodosa
Description A form of necrotizing non-granulomatous inflammation occurring primarily in medium-sized ARTERIES, often with microaneurysms. It is characterized by muscle, joint, and abdominal pain resulting from arterial infarction and scarring in affected organs. Polyarteritis nodosa with lung involvement is called CHURG-STRAUSS SYNDROME. [MeSH]
MedDRA Code 10036024
MeSH ID D010488
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE) Not Available
Synonym
Classic polyarteritis nodosa | Kussmaul's disease | Panarteritis nodosa | Periarteritis nodos with necrosis | Periarteritis nodosa | Periarteritis nodosa with necrosis | Polyarteritis nodosa | Polyarteritis nodosa and allied conditions | Polyarteritis nodosa of childhood | Polyarteritis nodosum | Polyarteritis Nodosa | Periarteritis Nodosa | Necrotizing Arteritis | Arteritides, Necrotizing | Arteritis, Necrotizing | Necrotizing Arteritides | Essential Polyarteritis | Essential Polyarteritides | Polyarteritides, Essential | Polyarteritis, Essential
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00029Acetyl sulfisoxazole--
BADD_D00499Clomipramine--
BADD_D00500Clomipramine hydrochloride--
BADD_D01063Hepatitis b vaccine--
BADD_D01167Interferon alfa-2b--
BADD_D01414Methimazole--
BADD_D01418Methotrexate0.000114%
BADD_D01470Minocycline0.006966%
BADD_D01567Nilotinib0.000112%
BADD_D01765Phenytoin--
BADD_D01766Phenytoin sodium--
BADD_D02090Sulfadiazine--
BADD_D02091Sulfamethoxazole--
BADD_D02093Sulfasalazine--
BADD_D02436Atorvastatin--
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