Adverse Drug Reaction Classification System

ADR Ontology
ADR Term Pre-eclampsia
ADR ID BADD_A03526
ADR Hierarchy
18      Pregnancy, puerperium and perinatal conditions
18.02      Maternal complications of pregnancy
18.02.03      Hypertension associated disorders of pregnancy
18.02.03.002      Pre-eclampsia
20      Renal and urinary disorders
20.01      Renal disorders (excl nephropathies)
20.01.08      Renal hypertension and related conditions
20.01.08.002      Pre-eclampsia
24      Vascular disorders
24.08      Vascular hypertensive disorders
24.08.07      Pregnancy associated hypertension
24.08.07.002      Pre-eclampsia
Description A complication of PREGNANCY, characterized by a complex of symptoms including maternal HYPERTENSION and PROTEINURIA with or without pathological EDEMA. Symptoms may range between mild and severe. Pre-eclampsia usually occurs after the 20th week of gestation, but may develop before this time in the presence of trophoblastic disease. [MeSH]
MedDRA Code 10036485
MeSH ID D011225
ADR Severity Grade (FAERS) Not Available
ADR Severity Grade (CTCAE) Not Available
Synonym
Mild or unspecified pre-eclampsia | Mild or unspecified pre-eclampsia, antepartum | Mild or unspecified pre-eclampsia, postpartum | Mild or unspecified pre-eclampsia, unspecified as to episode of care | Mild or unspecified pre-eclampsia, with delivery | Mild or unspecified pre-eclampsia, with delivery, with mention of postpartum complication | Pre-eclampsia | Pre-eclampsia toxemia | Pre-eclamptic toxaemia | Severe pre-eclampsia | Severe pre-eclampsia, antepartum | Severe pre-eclampsia, postpartum | Severe pre-eclampsia, unspecified as to episode of care | Severe pre-eclampsia, with delivery | Severe pre-eclampsia, with delivery, with mention of postpartum complication | Toxaemia of pregnancy | Toxemia of pregnancy | Pre-eclampsia aggravated | Gestosis | Pre-eclampsia toxaemia | Pre-eclampsia with severe features | Preeclampsia | Pre-Eclampsia | Pre Eclampsia | Pregnancy Toxemias | Pregnancy Toxemia | Toxemia, Pregnancy | Edema-Proteinuria-Hypertension Gestosis | Edema Proteinuria Hypertension Gestosis | Gestosis, Edema-Proteinuria-Hypertension | Hypertension-Edema-Proteinuria Gestosis | Gestosis, Hypertension-Edema-Proteinuria | Hypertension Edema Proteinuria Gestosis | Toxemia Of Pregnancy | Of Pregnancies, Toxemia | Of Pregnancy, Toxemia | Pregnancies, Toxemia Of | Pregnancy, Toxemia Of | Toxemia Of Pregnancies | EPH Complex | EPH Toxemias | EPH Toxemia | Toxemia, EPH | Toxemias, EPH | EPH Gestosis | Gestosis, EPH | Toxemias, Pregnancy | Preeclampsia Eclampsia 1 | 1, Preeclampsia Eclampsia | 1s, Preeclampsia Eclampsia | Eclampsia 1, Preeclampsia | Eclampsia 1s, Preeclampsia | Preeclampsia Eclampsia 1s | Proteinuria-Edema-Hypertension Gestosis | Gestosis, Proteinuria-Edema-Hypertension | Proteinuria Edema Hypertension Gestosis
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00023Acetaminophen--
BADD_D00033Acetylsalicylic acid0.000055%
BADD_D00056Albuterol--
BADD_D00165Aripiprazole0.000119%
BADD_D00310Buprenorphine0.000543%
BADD_D00499Clomipramine0.002898%
BADD_D00551Cyclosporine0.000166%
BADD_D00594Deferasirox0.001239%
BADD_D00648Diazepam0.000050%
BADD_D00668Digoxin0.000211%
BADD_D00704Dolutegravir sodium0.000423%
BADD_D00749Efavirenz0.009175%
BADD_D00809Escitalopram0.000028%
BADD_D00932Fluoxetine0.000335%
BADD_D00979Furosemide0.000028%
BADD_D01106Hydroxyprogesterone--
BADD_D01107Hydroxyprogesterone caproate-
BADD_D01236Labetalol0.000650%
BADD_D01243Lamotrigine0.000055%
BADD_D01265Levetiracetam0.001471%
BADD_D01281Levonorgestrel0.001418%
BADD_D01401Metformin0.000022%
BADD_D01425Methyldopa0.002054%
BADD_D01431Methylphenidate0.000103%
BADD_D01476Mirtazapine0.000200%
BADD_D01564Nicotine0.001567%
BADD_D01566Nifedipine0.000187%
BADD_D01599Olanzapine0.000316%
BADD_D01617Ondansetron0.000079%
BADD_D01653Paclitaxel0.000112%
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ADReCS-Target
ADR Term Drug Name Target