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ADR Term
ADReCS ID
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ADR Ontology
ADR Term
Premature rupture of membranes
ADR ID
BADD_A03540
ADR Hierarchy
18
Pregnancy, puerperium and perinatal conditions
18.07
Maternal complications of labour and delivery
18.07.01
Labour onset and length abnormalities
18.07.01.003
Premature rupture of membranes
Description
Not Available
MedDRA Code
10036603
MeSH ID
Not Available
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE)
Not Available
Synonym
Premature rupture of membranes | Premature rupture of membranes affecting fetus or newborn | Premature rupture of membranes, antepartum | Premature rupture of membranes, delivered | Premature rupture of membranes, unspecified as to episode of care
Drugs Leading to the ADR
Drug ID
Drug Name
ADR Frequency (FAERS)
ADR Severity Grade (FAERS)
BADD_D00033
Acetylsalicylic acid
0.000022%
BADD_D00085
Alprazolam
0.000019%
BADD_D00165
Aripiprazole
0.000396%
BADD_D00195
Azathioprine
0.000783%
BADD_D00209
Baclofen
0.000070%
BADD_D00356
Carbamazepine
0.000279%
BADD_D00407
Cefuroxime
0.000143%
BADD_D00501
Clonazepam
0.000030%
BADD_D00504
Clopidogrel
0.000021%
BADD_D00668
Digoxin
0.000105%
BADD_D00682
Dinoprost
-
-
BADD_D00684
Dinoprostone
-
-
BADD_D00704
Dolutegravir sodium
0.000282%
BADD_D00749
Efavirenz
0.003670%
BADD_D00932
Fluoxetine
0.000152%
BADD_D00952
Folic acid
-
-
BADD_D01106
Hydroxyprogesterone
-
-
BADD_D01107
Hydroxyprogesterone caproate
-
BADD_D01110
Hydroxyurea
0.000168%
BADD_D01236
Labetalol
0.000244%
BADD_D01238
Lacosamide
0.002194%
BADD_D01243
Lamotrigine
0.000276%
BADD_D01252
Leflunomide
0.000428%
BADD_D01265
Levetiracetam
0.000556%
BADD_D01281
Levonorgestrel
0.002364%
BADD_D01401
Metformin
0.000005%
BADD_D01477
Misoprostol
0.001541%
BADD_D01564
Nicotine
0.000940%
BADD_D01566
Nifedipine
0.000075%
BADD_D01599
Olanzapine
0.000210%
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