Adverse Drug Reaction Classification System

ADR Ontology
ADR Term Productive cough
ADR ID BADD_A03556
ADR Hierarchy
22      Respiratory, thoracic and mediastinal disorders
22.02      Respiratory disorders NEC
22.02.03      Coughing and associated symptoms
22.02.03.005      Productive cough
Description A disorder characterized by expectorated secretions upon coughing. [CTCAE] Material coughed up from the lungs and expectorated via the mouth. It contains MUCUS, cellular debris, and microorganisms. It may also contain blood or pus. [MeSH]
MedDRA Code 10036790
MeSH ID D013183
ADR Severity Grade (FAERS) Not Available
ADR Severity Grade (CTCAE)
Synonym
Productive cough | Sputum | Expectoration | Phlegm | Mucoid sputum | Sputums | Sputum, Induced | Induced Sputum | Induced Sputums | Sputums, Induced
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D01783Pirfenidone0.006920%
BADD_D01798Pomalidomide--
BADD_D01802Porfimer--
BADD_D01803Porfimer sodium--
BADD_D01817Pramipexole0.000159%
BADD_D01818Pramipexole dihydrochloride--
BADD_D01831Prednisolone0.000217%
BADD_D01834Prednisone0.000082%
BADD_D01867Propranolol0.000262%
BADD_D01909Ramipril0.000373%
BADD_D01913Ranitidine--
BADD_D01922Regorafenib0.001164%
BADD_D01933Ribavirin0.024526%
BADD_D01948Riociguat0.001095%
BADD_D01951Risperidone--
BADD_D01962Roflumilast0.001570%
BADD_D01971Rosuvastatin--
BADD_D02006Selexipag0.000666%
BADD_D02047Sodium oxybate0.004104%
BADD_D02093Sulfasalazine0.000818%
BADD_D02100Sunitinib0.001186%
BADD_D02105Tacrolimus--
BADD_D02106Tadalafil0.000488%
BADD_D02107Tafamidis0.001077%
BADD_D02145Telbivudine--
BADD_D02150Temozolomide0.000168%
BADD_D02174Testosterone undecanoate-
BADD_D02232Tobramycin0.002958%
BADD_D02236Tofacitinib0.033828%
BADD_D02247Topiramate0.000286%
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