Adverse Drug Reaction Classification System

         

ADR Ontology
ADR Term Purpura
ADR ID BADD_A03668
ADR Hierarchy
01      Blood and lymphatic system disorders
01.01      Coagulopathies and bleeding diatheses (excl thrombocytopenic)
01.01.04      Purpuras (excl thrombocytopenic)
01.01.04.003      Purpura
23      Skin and subcutaneous tissue disorders
23.06      Skin vascular abnormalities
23.06.01      Purpura and related conditions
23.06.01.004      Purpura
24      Vascular disorders
24.07      Vascular haemorrhagic disorders
24.07.06      Bruising, ecchymosis and purpura
24.07.06.005      Purpura
Description A disorder characterized by hemorrhagic areas of the skin and mucous membrane. Newer lesions appear reddish in color. Older lesions are usually a darker purple color and eventually become a brownish-yellow color. [CTCAE] Purplish or brownish red discoloration, easily visible through the epidermis, caused by hemorrhage into the tissues. When the size of the discolorization is >2-3 cm it is generally called Ecchymoses (ECCHYMOSIS). | Pinhead size (3 mm) skin discolorization due to hemorrhage. [MeSH]
MedDRA Code 10037549
MeSH ID D011693
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE)
Synonym
Dermatitis haemorrhagic | Dermatitis hemorrhagic | Haemolytic type rash | Haemorrhage purpuric | Idiopathic purpura | Purpura | Purpura NOS | Purpuric rash | Rash haemorrhagic | Rash hemorrhagic | Rash purpitic | Rash purpuric | Purpura symptomatica | Hemorrhage purpuric | Hemolytic type rash | Wet purpura | Dry purpura | Retiform purpura | Mechanical purpura | Purpuras | Petechiae
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00950Fluvoxamine--
BADD_D00951Fluvoxamine maleate--
BADD_D00957Fondaparinux sodium--
BADD_D00967Fosinopril--
BADD_D00971Fosphenytoin sodium--
BADD_D00974Fragmin--
BADD_D00976Frovatriptan--
BADD_D00977Frovatriptan succinate--
BADD_D00979Furosemide0.000028%
BADD_D00981Gabapentin--
BADD_D00996Galantamine--
BADD_D00997Galantamine hydrobromide--
BADD_D01009Gemcitabine0.000168%
BADD_D01016Gentamicin--
BADD_D01021Glatiramer acetate--
BADD_D01030Glyburide--
BADD_D01046Guanfacine--
BADD_D01047Guanfacine hydrochloride--
BADD_D01048Guanidine--
BADD_D01049Guanidine hydrochloride--
BADD_D01060Heparin--
BADD_D01064Hepatitis b vaccine (recombinant)--
BADD_D01081Hydralazine0.000184%
BADD_D01082Hydralazine hydrochloride--
BADD_D01083Hydrochlorothiazide--
BADD_D01088Hydrocortisone butyrate--
BADD_D01093Hydroflumethiazide--
BADD_D01103Hydroxychloroquine0.007438%
BADD_D01104Hydroxychloroquine sulfate--
BADD_D01119Ibrutinib0.001892%
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