Adverse Drug Reaction Classification System

         

ADR Ontology
ADR Term Renal papillary necrosis
ADR ID BADD_A03764
ADR Hierarchy
05      Endocrine disorders
05.07      Diabetic complications
05.07.02      Diabetic complications renal
05.07.02.001      Renal papillary necrosis
14      Metabolism and nutrition disorders
14.07      Diabetic complications
14.07.02      Diabetic complications renal
14.07.02.001      Renal papillary necrosis
20      Renal and urinary disorders
20.01      Renal disorders (excl nephropathies)
20.01.07      Renal vascular and ischaemic conditions
20.01.07.002      Renal papillary necrosis
Description A complication of kidney diseases characterized by cell death involving KIDNEY PAPILLA in the KIDNEY MEDULLA. Damages to this area may hinder the kidney to concentrate urine resulting in POLYURIA. Sloughed off necrotic tissue may block KIDNEY PELVIS or URETER. Necrosis of multiple renal papillae can lead to KIDNEY FAILURE. [MeSH]
MedDRA Code 10038491
MeSH ID D007681
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE) Not Available
Synonym
Acute papillary necrosis | Necrosis kidney papillary | Necrosis papillary kidney | Nephritis and nephropathy, not spec as acute or chronic, with lesion of renal medullary necrosis | Papillary kidney necrosis | Papillary necrosis renal | Papillitis renal necrotizing | Renal medullary necrosis | Renal papillary necrosis | Renal papillitis | Renal papillitis necrotising | Renal papillitis necrotizing | Papillitis renal necrotising | Kidney Papillary Necrosis | Necrosis, Kidney Papillary | Papillary Necrosis, Kidney | Renal Papillitis, Necrotizing | Necrotizing Renal Papillitides | Necrotizing Renal Papillitis | Papillitides, Necrotizing Renal | Renal Papillitides, Necrotizing | Renal Medullary Necrosis | Necrosis, Renal Medullary
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00033Acetylsalicylic acid0.000022%
BADD_D00405Ceftriaxone0.004457%
BADD_D00580Dapsone--
BADD_D00594Deferasirox0.001239%
BADD_D00850Etodolac--
BADD_D00877Fenoprofen--
BADD_D00878Fenoprofen calcium--
BADD_D01120Ibuprofen--
BADD_D01368Mefenamic acid--
BADD_D01533Naproxen--
BADD_D01534Naproxen sodium--
BADD_D02367Voltaren--
The 1th Page    1    Total 1 Pages