Adverse Drug Reaction Classification System

ADR Ontology
ADR Term Respiratory failure
ADR ID BADD_A03813
ADR Hierarchy
14      Metabolism and nutrition disorders
14.01      Acid-base disorders
14.01.04      Respiratory acidoses
14.01.04.003      Respiratory failure
22      Respiratory, thoracic and mediastinal disorders
22.02      Respiratory disorders NEC
22.02.06      Respiratory failures (excl neonatal)
22.02.06.002      Respiratory failure
Description A disorder characterized by impaired gas exchange by the respiratory system resulting in hypoxia and a decrease in oxygenation of the tissues that may be associated with an increase in arterial levels of carbon dioxide. [CTCAE] Failure to adequately provide oxygen to cells of the body and to remove excess carbon dioxide from them. (Stedman, 25th ed) [MeSH]
MedDRA Code 10038695
MeSH ID D012131
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE)
Synonym
Failure respiratory | Other pulmonary insufficiency, not elsewhere classified | Pulmonary insufficiency following trauma and surgery | Respiration failure | Respiratory failure | Respiratory failure (excl neonatal) | Respiratory insufficiency | Ventilatory failure | Pulmonary failure | Hypercapnic respiratory failure | Restrictive respiratory insufficiency | Respiratory failure aggravated | Hypoxic respiratory failure | End stage lung disease | Respiratory failure type 1 | Respiratory failure type 2 | Hypoxemic respiratory failure | Hypoxaemic respiratory failure | Respiratory Insufficiency | Respiratory Failure | Respiratory Depression | Ventilatory Depression | Depressions, Ventilatory
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D01352Maraviroc0.000988%
BADD_D01376Melphalan0.000504%
BADD_D01378Memantine0.000363%
BADD_D01393Meropenem0.000243%
BADD_D01401Metformin0.000544%
BADD_D01405Methadone0.006285%
BADD_D01414Methimazole0.000405%
BADD_D01415Methocarbamol0.000135%
BADD_D01418Methotrexate--
BADD_D01419Methotrexate sodium--
BADD_D01431Methylphenidate--
BADD_D01433Methylprednisolone0.000310%
BADD_D01442Metoclopramide--
BADD_D01445Metoprolol0.000050%
BADD_D01450Metyrapone0.000198%
BADD_D01455Micafungin0.000150%
BADD_D01459Midazolam--
BADD_D01465Miglustat0.025874%
BADD_D01470Minocycline0.000767%
BADD_D01478Mitomycin0.000224%
BADD_D01498Morphine0.002751%
BADD_D01506Muromonab-cd3--
BADD_D01507Mycophenolate mofetil--
BADD_D01508Mycophenolic acid0.002378%
BADD_D01525Naloxone0.000973%
BADD_D01564Nicotine0.002507%
BADD_D01566Nifedipine0.000224%
BADD_D01572Nitisinone0.006469%
BADD_D01574Nitric oxide-
BADD_D01576Nitrofurantoin0.000083%
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