Adverse Drug Reaction Classification System

         

ADR Ontology
ADR Term Retinopathy of prematurity
ADR ID BADD_A03869
ADR Hierarchy
18      Pregnancy, puerperium and perinatal conditions
18.04      Neonatal and perinatal conditions
18.04.01      Newborn complications NEC
18.04.01.004      Retinopathy of prematurity
06      Eye disorders
06.10      Retina, choroid and vitreous haemorrhages and vascular disorders
06.10.02      Retinopathies NEC
06.10.02.012      Retinopathy of prematurity
12      Injury, poisoning and procedural complications
12.02      Procedural related injuries and complications NEC
12.02.02      Eye and ear procedural complications
12.02.02.015      Retinopathy of prematurity
Description A bilateral retinopathy occurring in premature infants treated with excessively high concentrations of oxygen, characterized by vascular dilatation, proliferation, and tortuosity, edema, and retinal detachment, with ultimate conversion of the retina into a fibrous mass that can be seen as a dense retrolental membrane. Usually growth of the eye is arrested and may result in microophthalmia, and blindness may occur. (Dorland, 27th ed) [MeSH]
MedDRA Code 10038933
MeSH ID D012178
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE) Not Available
Synonym
Retinopathy of prematurity | Retrolental fibro-dysplasia | Retrolental fibroplasia | Immature retinal vascularisation | Immature retinal vascularization | Retinal immaturity | Progressive retinopathy of prematurity | Retinopathy of Prematurity | Prematurity Retinopathies | Prematurity Retinopathy | Retrolental Fibroplasia | Fibroplasia, Retrolental | Fibroplasias, Retrolental | Retrolental Fibroplasias
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00332Caffeine--
BADD_D00333Caffeine citrate--
BADD_D00623Dexamethasone--
BADD_D00624Dexamethasone phosphate--
BADD_D00912Fluconazole0.000045%
BADD_D00932Fluoxetine0.000020%
BADD_D01120Ibuprofen0.000026%
BADD_D01156Indomethacin0.003891%
BADD_D02010Sertraline0.000013%
BADD_D02471Oxygen0.023543%
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