Adverse Drug Reaction Classification System

         

ADR Ontology
ADR Term Rheumatoid arthritis
ADR ID BADD_A03878
ADR Hierarchy
10      Immune system disorders
10.04      Autoimmune disorders
10.04.06      Rheumatoid arthritis and associated conditions
10.04.06.001      Rheumatoid arthritis
15      Musculoskeletal and connective tissue disorders
15.01      Joint disorders
15.01.03      Rheumatoid arthropathies
15.01.03.001      Rheumatoid arthritis
Description A chronic systemic disease, primarily of the joints, marked by inflammatory changes in the synovial membranes and articular structures, widespread fibrinoid degeneration of the collagen fibers in mesenchymal tissues, and by atrophy and rarefaction of bony structures. Etiology is unknown, but autoimmune mechanisms have been implicated. [MeSH]
MedDRA Code 10039073
MeSH ID D001172
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE) Not Available
Synonym
Arthritis rheumatoid | Arthritis rheumatoid aggravated | Chronic postrheumatic arthropathy | Monoarthritic rheumatoid arthritis | Other rheumatoid arthritis with visceral or systemic involvement | Proliferative arthritis | R arthritis | RA | Rh arthritis | Rheumatoid arthritis | Rheumatoid arthritis aggravated | Rheumatoid arthritis and other inflammatory polyarthropathies | Rheumatoid arthropathy | Seropositive RA | Seropositive rheumatoid arthritis | Systemic rheumatoid arthritis | Chronic post rheumatic arthropathy | Rheumatoid arthritis flare up | Seronegative rheumatoid arthritis | Progression of rheumatoid arthritis | Rheumatic arthritis acute | Spinal rheumatoid arthritis | Rheumatoid arthritis in remission | Rheumatoid arthritis relapse | Rheumatoid polyarthritis | Arthritis, Rheumatoid | Rheumatoid Arthritis
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D02093Sulfasalazine0.003637%
BADD_D02099Sumatriptan succinate--
BADD_D02105Tacrolimus0.001693%
BADD_D02107Tafamidis0.000808%
BADD_D02154Tenofovir0.006204%
BADD_D02165Teriflunomide--
BADD_D02236Tofacitinib0.110405%
BADD_D02246Tolvaptan--
BADD_D02254Tramadol--
BADD_D02331Valsartan0.000169%
BADD_D02337Varenicline0.000623%
BADD_D02346Venlafaxine0.000048%
BADD_D02367Voltaren--
BADD_D02375Water--
BADD_D02392Zoledronic acid0.012883%
BADD_D02397Zopiclone--
BADD_D02407Upadacitinib0.011790%
BADD_D02443Tiotropium0.000339%
BADD_D02452Icatibant-
BADD_D02470Nintedanib0.000526%
BADD_D02487Baricitinib0.006944%
BADD_D02539Calcium0.000861%
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ADReCS-Target
ADR Term Drug Name Target