Adverse Drug Reaction Classification System

         

ADR Ontology
ADR Term Rubber sensitivity
ADR ID BADD_A03900
ADR Hierarchy
10      Immune system disorders
10.01      Allergic conditions
10.01.01      Allergies to foods, food additives, drugs and other chemicals
10.01.01.025      Rubber sensitivity
23      Skin and subcutaneous tissue disorders
23.03      Epidermal and dermal conditions
23.03.04      Dermatitis and eczema
23.03.04.036      Rubber sensitivity
Description Allergic reaction to products containing processed natural rubber latex such as rubber gloves, condoms, catheters, dental dams, balloons, and sporting equipment. Both T-cell mediated (HYPERSENSITIVITY, DELAYED) and IgE antibody-mediated (HYPERSENSITIVITY, IMMEDIATE) allergic responses are possible. Delayed hypersensitivity results from exposure to antioxidants present in the rubber; immediate hypersensitivity results from exposure to a latex protein. [MeSH]
MedDRA Code 10039251
MeSH ID D020315
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE) Not Available
Synonym
Rubber sensitivity | Latex allergy | Synthetic rubber sensitivity | Latex Hypersensitivity | Hypersensitivities, Latex | Latex Hypersensitivities | Hypersensitivity, Latex | Rubber Latex Allergy | Allergies, Rubber Latex | Allergy, Rubber Latex | Rubber Latex Allergies | Natural Rubber Latex Allergy | Rubber Allergy | Allergies, Rubber | Allergy, Rubber | Rubber Allergies | Allergy, Latex | Latex Allergy | Allergies, Latex | Latex Allergies
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00310Buprenorphine0.001847%
BADD_D00312Bupropion--
BADD_D00382Cefazolin0.000165%
BADD_D00417Cetirizine--
BADD_D00483Clindamycin--
BADD_D01418Methotrexate--
BADD_D01834Prednisone--
BADD_D02375Water--
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