Adverse Drug Reaction Classification System

         

ADR Ontology
ADR Term Sepsis
ADR ID BADD_A03968
ADR Hierarchy
11      Infections and infestations
11.01      Infections - pathogen unspecified
11.01.11      Sepsis, bacteraemia, viraemia and fungaemia NEC
11.01.11.003      Sepsis
Description A disorder characterized by the presence of pathogenic microorganisms in the blood stream that cause a rapidly progressing systemic reaction that may lead to shock. [CTCAE] Systemic inflammatory response syndrome with a proven or suspected infectious etiology. When sepsis is associated with organ dysfunction distant from the site of infection, it is called severe sepsis. When sepsis is accompanied by HYPOTENSION despite adequate fluid infusion, it is called SEPTIC SHOCK. | Sepsis associated with organ dysfunction distant from the site of infection. | Septicemia caused by pyogenic microorganisms (e.g., STAPHYLOCOCCUS; BACILLUS), resulting in the formation of secondary foci of SUPPURATION and multiple ABSCESSES. | Systemic disease associated with the presence of pathogenic microorganisms or their toxins in the blood. [MeSH]
MedDRA Code 10040047
MeSH ID D018805
ADR Severity Grade (FAERS) Not Available
ADR Severity Grade (CTCAE)
Synonym
Other specified septicaemias | Other specified septicemias | Pyaemia | Pyemia | Sepsis | Sepsis NOS | Sepsis secondary | Septicaemia | Septicaemia NOS | Septicemia | Unspecified septicemia | Septicopyemia | Septicopyaemia | Unspecified septicaemia | Severe Sepsis | Sepsis, Severe | Pyemias | Pyohemia | Pyohemias | Pyaemias | Septicemias | Poisoning, Blood | Blood Poisoning | Blood Poisonings | Poisonings, Blood
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00047Afatinib--
BADD_D00049Agalsidase beta--
BADD_D00062Aldesleukin--
BADD_D00064Alemtuzumab--
BADD_D00075Alitretinoin--
BADD_D00076Allopurinol--
BADD_D00086Alprostadil--
BADD_D00087Alteplase--
BADD_D00132Amphotericin b--
BADD_D00137Amsacrine--
BADD_D00143Anidulafungin--
BADD_D00146Anti-thymocyte globulin (rabbit)--
BADD_D00158Aprotinin (bovine)--
BADD_D00161Argatroban--
BADD_D00168Arsenic--
BADD_D00169Arsenic trioxide--
BADD_D00194Azacitidine--
BADD_D00207Bacillus calmette-guerin--
BADD_D00209Baclofen--
BADD_D00213Barium sulfate--
BADD_D00214Basiliximab--
BADD_D00230Bendamustine--
BADD_D00231Bendamustine hydrochloride--
BADD_D00255Beractant--
BADD_D00269Bexarotene--
BADD_D00271Bicalutamide--
BADD_D00279Bivalirudin--
BADD_D00282Blinatumomab--
BADD_D00283Boceprevir--
BADD_D00284Bortezomib--
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