Adverse Drug Reaction Classification System

ADR Ontology
ADR Term Spinal cord compression
ADR ID BADD_A04126
ADR Hierarchy
17      Nervous system disorders
17.10      Spinal cord and nerve root disorders
17.10.01      Spinal cord and nerve root disorders NEC
17.10.01.006      Spinal cord compression
Description A disorder characterized by pressure on the spinal cord. [CTCAE] Acute and chronic conditions characterized by external mechanical compression of the SPINAL CORD due to extramedullary neoplasm; EPIDURAL ABSCESS; SPINAL FRACTURES; bony deformities of the vertebral bodies; and other conditions. Clinical manifestations vary with the anatomic site of the lesion and may include localized pain, weakness, sensory loss, incontinence, and impotence. [MeSH]
MedDRA Code 10041549
MeSH ID D013117
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE)
Synonym
Spinal cord compression | Spinal cord compression NOS | Thoracic spinal cord compression | Spinal Cord Compression | Compression, Spinal Cord | Compressions, Spinal Cord | Spinal Cord Compressions | Myelopathy, Compressive | Compressive Myelopathy | Spinal Cord Compression, Extramedullary | Extramedullary Spinal Cord Compression | Conus Medullaris Syndrome | Conus Medullaris Syndromes | Syndrome, Conus Medullaris | Syndromes, Conus Medullaris
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00014Abiraterone0.001502%
BADD_D00047Afatinib0.000224%
BADD_D00066Alendronic acid0.000066%
BADD_D00151Apixaban0.000195%
BADD_D00193Axitinib0.000224%
BADD_D00209Baclofen0.000070%
BADD_D00271Bicalutamide0.004218%
BADD_D00284Bortezomib0.000470%
BADD_D00315Buserelin acetate--
BADD_D00330Cabozantinib0.000302%
BADD_D00364Carboplatin0.000112%
BADD_D00405Ceftriaxone0.006685%
BADD_D00504Clopidogrel0.000225%
BADD_D00563Dabigatran0.000783%
BADD_D00623Dexamethasone0.000291%
BADD_D00775Enzalutamide0.001668%
BADD_D00858Everolimus0.000306%
BADD_D01038Goserelin--
BADD_D01119Ibrutinib0.000112%
BADD_D01136Imatinib0.000112%
BADD_D01180Iohexol0.007113%
BADD_D01253Lenalidomide0.004798%
BADD_D01260Leuprolide acetate--
BADD_D01261Leuprolide monoacetate--
BADD_D01336Macitentan0.000120%
BADD_D01378Memantine0.000121%
BADD_D01498Morphine0.000278%
BADD_D01567Nilotinib0.000112%
BADD_D01676Paricalcitol0.001962%
BADD_D01687Pazopanib0.000280%
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