Adverse Drug Reaction Classification System

ADR Ontology
ADR Term Splenomegaly
ADR ID BADD_A04138
ADR Hierarchy
01      Blood and lymphatic system disorders
01.09      Spleen, lymphatic and reticuloendothelial system disorders
01.09.02      Spleen disorders
01.09.02.001      Splenomegaly
Description Enlargement of the spleen. [MeSH]
MedDRA Code 10041660
MeSH ID D013163
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE) Not Available
Synonym
Chronic congestive splenomegaly | Spleen dullness enlarged | Spleen enlarged | Splenomegaly | Megalosplenia | Hypersplenotrophy | Enlarged Spleen | Spleen, Enlarged
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00623Dexamethasone0.000145%
BADD_D00680Dimethyl fumarate0.005761%
BADD_D00749Efavirenz0.003670%
BADD_D00759Eltrombopag0.000617%
BADD_D00788Epoprostenol0.000329%
BADD_D00789Epoprostenol sodium--
BADD_D00870Febuxostat--
BADD_D00897Filgrastim--
BADD_D00898Finasteride0.000135%
BADD_D00914Fludarabine0.000336%
BADD_D00931Fluorouracil0.000551%
BADD_D01003Ganciclovir--
BADD_D01016Gentamicin--
BADD_D01020Glatiramer--
BADD_D01021Glatiramer acetate--
BADD_D01062Hepatitis b immune globulin (human)--
BADD_D01081Hydralazine--
BADD_D01082Hydralazine hydrochloride--
BADD_D01103Hydroxychloroquine0.002789%
BADD_D01110Hydroxyurea0.001869%
BADD_D01119Ibrutinib0.002451%
BADD_D01130Idelalisib0.000224%
BADD_D01136Imatinib0.001869%
BADD_D01167Interferon alfa-2b--
BADD_D01197Iron--
BADD_D01204Isoniazid--
BADD_D01242Lamivudine--
BADD_D01243Lamotrigine0.000635%
BADD_D01252Leflunomide0.000428%
BADD_D01253Lenalidomide--
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