Adverse Drug Reaction Classification System

         

ADR Ontology
ADR Term Stress fracture
ADR ID BADD_A04167
ADR Hierarchy
12      Injury, poisoning and procedural complications
12.04      Bone and joint injuries
12.04.02      Fractures and dislocations NEC
12.04.02.003      Stress fracture
15      Musculoskeletal and connective tissue disorders
15.08      Fractures
15.08.02      Fractures NEC
15.08.02.002      Stress fracture
Description Fractures due to the strain caused by repetitive exercise. They are thought to arise from a combination of MUSCLE FATIGUE and bone failure, and occur in situations where BONE REMODELING predominates over repair. The most common sites of stress fractures are the METATARSUS; FIBULA; TIBIA; and FEMORAL NECK. | A form of stress fractures that result when normal force is applied to bones with deficient elasticity. [MeSH]
MedDRA Code 10042212
MeSH ID D015775
ADR Severity Grade (FAERS) Not Available
ADR Severity Grade (CTCAE) Not Available
Synonym
March fracture | Stress fracture | Pelvic insufficiency fracture | Fatigue fracture | Insufficiency fracture | Subchondral insufficiency fracture | Hairline fracture | Capillary fracture | Sacral insufficiency fracture | Fractures, Stress | Fracture, Stress | Stress Fracture | Stress Fractures | Fractures, March | Fracture, March | March Fracture | March Fractures | Fatigue Fractures | Fatigue Fracture | Fracture, Fatigue | Fractures, Fatigue | Microfractures | Microfracture | Micro Fractures | Fracture, Micro | Fractures, Micro | Micro Fracture | Bone Stress Reaction | Bone Stress Reactions | Stress Reaction, Bone | Insufficiency Fractures | Fracture, Insufficiency | Insufficiency Fracture
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D01418Methotrexate--
BADD_D01419Methotrexate sodium--
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