Adverse Drug Reaction Classification System

         

ADR Ontology
ADR Term Syncope
ADR ID BADD_A04220
ADR Hierarchy
17      Nervous system disorders
17.02      Neurological disorders NEC
17.02.04      Disturbances in consciousness NEC
17.02.04.008      Syncope
24      Vascular disorders
24.06      Decreased and nonspecific blood pressure disorders and shock
24.06.02      Circulatory collapse and shock
24.06.02.012      Syncope
02      Cardiac disorders
02.11      Cardiac disorders, signs and symptoms NEC
02.11.04      Cardiac signs and symptoms NEC
02.11.04.015      Syncope
Description A disorder characterized by spontaneous loss of consciousness caused by insufficient blood supply to the brain. [CTCAE] A transient loss of consciousness and postural tone caused by diminished blood flow to the brain (i.e., BRAIN ISCHEMIA). Presyncope refers to the sensation of lightheadedness and loss of strength that precedes a syncopal event or accompanies an incomplete syncope. (From Adams et al., Principles of Neurology, 6th ed, pp367-9) [MeSH]
MedDRA Code 10042772
MeSH ID D013575; D019462
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE)
Synonym
Faint | Fainting | Swooning | Syncopal attack | Syncope | Syncope exertional | Syncope postural | Syncope vagovagal | Syncope vasovagal | Syncope aggravated | Orthostatic collapse | Syncope micturition | Syncope hypotensive | Syncope convulsive | Tussive syncope | Cardiac syncope | Neurally mediated syncope | Neurocardiogenic syncope | Swallow syncope | Cough syncope | Arrhythmic syncope | Cardiovascular syncope | Orthostatic syncope | Defecation syncope | Defaecation syncope | Syncopes | Presyncope | Presyncopes | Syncopal Episode | Episode, Syncopal | Syncopal Episodes | Syncopal Vertigo | Vertigo, Syncopal | Vertigos, Syncopal | Syncope, Cardiogenic | Cardiogenic Syncope | Cardiogenic Syncopes | Syncopes, Cardiogenic | Syncope, Carotid Sinus | Carotid Sinus Syncope | Carotid Sinus Syncopes | Syncopes, Carotid Sinus | Syncope, Convulsive | Convulsive Syncope | Convulsive Syncopes | Syncopes, Convulsive | Syncope, Deglutitional | Deglutitional Syncope | Deglutitional Syncopes | Syncopes, Deglutitional | Syncope, Effort | Effort Syncope | Effort Syncopes | Syncopes, Effort | Syncope, Hyperventilation | Hyperventilation Syncope | Hyperventilation Syncopes | Syncopes, Hyperventilation | Syncope, Micturition | Micturition Syncope | Micturition Syncopes | Syncopes, Micturition | Syncope, Postural | Postural Syncope | Postural Syncopes | Syncopes, Postural | Syncope, Situational | Situational Syncope | Situational Syncopes | Syncopes, Situational | Syncope, Stokes-Adams | Stokes-Adams Syncope | Stokes-Adams Syncopes | Syncope, Stokes Adams | Syncopes, Stokes-Adams | Syncope, Tussive | Syncopes, Tussive | Tussive Syncope | Tussive Syncopes | Drop Attack | Attack, Drop | Drop Attacks
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00374Carvedilol0.000450%
BADD_D00375Carvedilol phosphate--
BADD_D00378Cefaclor--
BADD_D00382Cefazolin--
BADD_D00390Cefotaxime0.000073%
BADD_D00395Cefpodoxime--
BADD_D00405Ceftriaxone0.049022%
BADD_D00407Cefuroxime0.000572%
BADD_D00410Celecoxib--
BADD_D00417Cetirizine0.000114%
BADD_D00418Cetirizine hydrochloride--
BADD_D00424Cevimeline--
BADD_D00425Cevimeline hydrochloride--
BADD_D00429Chlorambucil0.000224%
BADD_D00432Chlordiazepoxide--
BADD_D00438Chloroprocaine--
BADD_D00439Chloroprocaine hydrochloride--
BADD_D00440Chloroquine--
BADD_D00445Chlorpromazine--
BADD_D00448Chlorthalidone0.000522%
BADD_D00451Cholestyramine--
BADD_D00452Cholestyramine resin--
BADD_D00463Cidofovir--
BADD_D00464Cidofovir dihydrate--
BADD_D00465Cilazapril monohydrate--
BADD_D00466Cilostazol0.000300%
BADD_D00471Ciprofloxacin0.000021%
BADD_D00472Ciprofloxacin hydrochloride--
BADD_D00474Cisplatin0.001735%
BADD_D00475Citalopram0.000156%
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ADReCS-Target
ADR Term Drug Name Target