Adverse Drug Reaction Classification System

ADR Ontology
ADR Term Temporomandibular joint syndrome
ADR ID BADD_A04241
ADR Hierarchy
15      Musculoskeletal and connective tissue disorders
15.01      Joint disorders
15.01.08      Joint related disorders NEC
15.01.08.008      Temporomandibular joint syndrome
17      Nervous system disorders
17.14      Headaches
17.14.01      Headaches NEC
17.14.01.017      Temporomandibular joint syndrome
Description A symptom complex consisting of pain, muscle tenderness, clicking in the joint, and limitation or alteration of mandibular movement. The symptoms are subjective and manifested primarily in the masticatory muscles rather than the temporomandibular joint itself. Etiologic factors are uncertain but include occlusal dysharmony and psychophysiologic factors. [MeSH]
MedDRA Code 10043220
MeSH ID D013706; D013705
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE) Not Available
Synonym
Arthralgia of temporomandibular joint | Other specified temporomandibular joint disorders | Tempo mandibular joint dysfunc | Temporomandibular joint arthralgia | Temporomandibular joint disorder | Temporomandibular joint disorder NOS | Temporomandibular joint disorders | Temporomandibular joint disorders, unspecified | Temporomandibular joint syndrome | TMJ syndrome | Temporomandibular joint dysfunction | Costen's syndrome | Mandibular joint neuralgia | Temporomandibular Joint Dysfunction Syndrome | Myofascial Pain Dysfunction Syndrome, Temporomandibular Joint | TMJ Syndrome | Syndrome, TMJ | Costen's Syndrome | Costen Syndrome | Costens Syndrome | Syndrome, Costen's | Temporomandibular Joint Syndrome | Joint Syndrome, Temporomandibular | Syndrome, Temporomandibular Joint
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00066Alendronic acid0.000713%
BADD_D00156Apremilast0.001760%
BADD_D00284Bortezomib--
BADD_D00312Bupropion0.000018%
BADD_D00621Desvenlafaxine0.000178%
BADD_D00898Finasteride0.000234%
BADD_D00932Fluoxetine0.000030%
BADD_D01117Ibandronic acid0.003389%
BADD_D01213Isotretinoin0.000566%
BADD_D01253Lenalidomide0.003930%
BADD_D01835Pregabalin0.000052%
BADD_D02047Sodium oxybate0.000992%
BADD_D02236Tofacitinib0.002990%
BADD_D02254Tramadol--
BADD_D02337Varenicline0.000662%
BADD_D02392Zoledronic acid0.007730%
BADD_D02440Lisdexamfetamine0.000355%
BADD_D02464Fingolimod0.001302%
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