Adverse Drug Reaction Classification System

         

ADR Ontology
ADR Term Tetany
ADR ID BADD_A04262
ADR Hierarchy
05      Endocrine disorders
05.04      Parathyroid gland disorders
05.04.02      Hypoparathyroid disorders
05.04.02.003      Tetany
14      Metabolism and nutrition disorders
14.04      Bone, calcium, magnesium and phosphorus metabolism disorders
14.04.01      Calcium metabolism disorders
14.04.01.005      Tetany
15      Musculoskeletal and connective tissue disorders
15.05      Muscle disorders
15.05.03      Muscle related signs and symptoms NEC
15.05.03.013      Tetany
Description A disorder characterized by muscle twitches, cramps, and carpopedal spasm, and when severe, laryngospasm and seizures. This condition is associated with unstable depolarization of axonal membranes, primarily in the peripheral nervous system. Tetany usually results from HYPOCALCEMIA or reduced serum levels of MAGNESIUM that may be associated with HYPERVENTILATION; HYPOPARATHYROIDISM; RICKETS; UREMIA; or other conditions. (From Adams et al., Principles of Neurology, 6th ed, p1490) [MeSH]
MedDRA Code 10043380
MeSH ID D013746
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE) Not Available
Synonym
Carpo-pedal spasm | Generalised tetany | Hypocalcemic tetany | Spasm carpopedal | Tetany | Tetany hypocalcemic | Accoucheur's hand | Hyperventilation tetany | Hypocalcaemic tetany | Tetany hypocalcaemic | Generalized tetany | Tetanies | Tetanilla | Tetanillas | Tetany, Neonatal | Neonatal Tetanies | Neonatal Tetany | Tetanies, Neonatal | Spasmophilia | Spasmophilias
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00306Budesonide0.000093%
BADD_D00330Cabozantinib0.000246%
BADD_D00335Calcitonin--
BADD_D00356Carbamazepine0.000279%
BADD_D00363Carbonic acid--
BADD_D00405Ceftriaxone0.011141%
BADD_D00469Cinacalcet hydrochloride--
BADD_D00474Cisplatin--
BADD_D00477Citric acid0.024190%
BADD_D00603Delavirdine--
BADD_D00604Delavirdine mesylate--
BADD_D00643Diamminedichloroplatinum--
BADD_D00673Dihydrogen phosphate--
BADD_D00674Diltiazem--
BADD_D00684Dinoprostone--
BADD_D00809Escitalopram--
BADD_D00919Flumazenil--
BADD_D00931Fluorouracil0.000184%
BADD_D00950Fluvoxamine--
BADD_D00979Furosemide0.000014%
BADD_D00981Gabapentin0.000021%
BADD_D01016Gentamicin--
BADD_D01053Halofantrine hydrochloride--
BADD_D01242Lamivudine0.001012%
BADD_D01245Lansoprazole0.000199%
BADD_D01250Lasofoxifene--
BADD_D01260Leuprolide acetate0.004876%
BADD_D01285Levothyroxine0.000010%
BADD_D01352Maraviroc--
BADD_D01433Methylprednisolone0.000048%
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