Adverse Drug Reaction Classification System

ADR Ontology
ADR Term Toxic encephalopathy
ADR ID BADD_A04358
ADR Hierarchy
12      Injury, poisoning and procedural complications
12.03      Exposures, chemical injuries and poisoning
12.03.01      Poisoning and toxicity
12.03.01.027      Toxic encephalopathy
17      Nervous system disorders
17.13      Encephalopathies
17.13.01      Encephalopathies toxic and metabolic
17.13.01.004      Toxic encephalopathy
Description Neurologic disorders caused by exposure to toxic substances through ingestion, injection, cutaneous application, or other method. This includes conditions caused by biologic, chemical, and pharmaceutical agents. [MeSH]
MedDRA Code 10044221
MeSH ID D020258
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE) Not Available
Synonym
Encephalopathy aluminum | Encephalopathy toxic | Encephalopathy toxic acute | Encephalopathy toxic chronic | Toxic encephalopathy | Toxic induced encephalopathy | Drug-induced encephalopathy | Encephalopathy aluminium | Dialysis dementia | Acute toxic metabolic encephalopathy | Toxic metabolic encephalopathy | Neurotoxicity Syndromes | Neurotoxicity Syndrome | Syndrome, Neurotoxicity | Syndromes, Neurotoxicity | Neurotoxin Disorders | Neurotoxin Disorder | Neurotoxic Disorders | Neurotoxic Disorder | Neurotoxin Diseases | Neurotoxin Disease | Poisoning, Nervous System | Nervous System Poisonings | Poisonings, Nervous System | Nervous System Poisoning | Encephalopathy, Toxic | Encephalopathies, Toxic | Toxic Encephalopathies | Toxic Encephalopathy | Toxic Encephalitis | Encephalitides, Toxic | Encephalitis, Toxic | Toxic Encephalitides
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00039Acyclovir0.002174%
BADD_D00052Albendazole0.001691%
BADD_D00121Amlodipine0.000006%
BADD_D00129Amoxicillin0.000007%
BADD_D00130Amphetamine0.000161%
BADD_D00165Aripiprazole0.000159%
BADD_D00209Baclofen0.002486%
BADD_D00312Bupropion0.000037%
BADD_D00332Caffeine0.000092%
BADD_D00349Capecitabine0.000560%
BADD_D00356Carbamazepine0.000744%
BADD_D00364Carboplatin0.000224%
BADD_D00386Cefepime0.000243%
BADD_D00399Ceftazidime0.000073%
BADD_D00405Ceftriaxone0.040109%
BADD_D00551Cyclosporine0.000276%
BADD_D00596Deferoxamine--
BADD_D00648Diazepam0.000101%
BADD_D00668Digoxin0.000105%
BADD_D00695Disulfiram0.016995%
BADD_D00723Doxorubicin0.000224%
BADD_D00734Duloxetine0.000040%
BADD_D00765Empagliflozin0.000246%
BADD_D00802Ertapenem0.000267%
BADD_D00809Escitalopram0.000028%
BADD_D00914Fludarabine0.000168%
BADD_D00931Fluorouracil0.000368%
BADD_D00932Fluoxetine0.000020%
BADD_D01204Isoniazid0.005560%
BADD_D01240Lactulose0.000268%
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