Adverse Drug Reaction Classification System

         

ADR Ontology
ADR Term Type I hypersensitivity
ADR ID BADD_A04407
ADR Hierarchy
10      Immune system disorders
10.01      Allergic conditions
10.01.03      Allergic conditions NEC
10.01.03.006      Type I hypersensitivity
Description Hypersensitivity reactions which occur within minutes of exposure to challenging antigen due to the release of histamine which follows the antigen-antibody reaction and causes smooth muscle contraction and increased vascular permeability. [MeSH]
MedDRA Code 10045240
MeSH ID D006969
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE) Not Available
Synonym
Hypersensitivity type I | Hypersensitivity type I NOS | Immediate hypersensitivity | Immediate hypersensitivity reaction | Type I hypersensitivity | Hypersensitivity, Immediate | Hypersensitivities, Immediate | Immediate Hypersensitivities | Immediate Hypersensitivity | IgE-Mediated Hypersensitivity | Hypersensitivities, IgE-Mediated | Hypersensitivity, IgE-Mediated | IgE Mediated Hypersensitivity | IgE-Mediated Hypersensitivities | Hypersensitivity, Type I | Hypersensitivities, Type I | Type I Hypersensitivities | Atopic Hypersensitivity | Atopic Hypersensitivities | Hypersensitivities, Atopic | Hypersensitivity, Atopic | Type I Hypersensitivity
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00033Acetylsalicylic acid0.000022%
BADD_D00039Acyclovir--
BADD_D00056Albuterol--
BADD_D00110Aminolevulinic acid0.000381%
BADD_D00115Amiodarone0.000135%
BADD_D00129Amoxicillin0.000251%
BADD_D00306Budesonide0.000233%
BADD_D00364Carboplatin0.001623%
BADD_D00382Cefazolin0.000073%
BADD_D00405Ceftriaxone0.004457%
BADD_D00407Cefuroxime0.000501%
BADD_D00410Celecoxib0.000050%
BADD_D00412Cephalexin0.000034%
BADD_D00434Chlorhexidine--
BADD_D00448Chlorthalidone0.000201%
BADD_D00460Ciclesonide--
BADD_D00474Cisplatin0.000224%
BADD_D00480Clarithromycin0.000223%
BADD_D00494Clodronic acid--
BADD_D00537Cromoglycate--
BADD_D00539Cromolyn sodium--
BADD_D00580Dapsone0.000367%
BADD_D00623Dexamethasone0.000145%
BADD_D00648Diazepam--
BADD_D00653Diclofenac0.000256%
BADD_D00854Etoposide0.000280%
BADD_D00858Everolimus0.000306%
BADD_D00962Fosaprepitant--
BADD_D00963Fosaprepitant dimeglumine--
BADD_D00984Gadobutrol0.007113%
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