Adverse Drug Reaction Classification System

ADR Ontology
ADR Term Type I hypersensitivity
ADR ID BADD_A04407
ADR Hierarchy
10      Immune system disorders
10.01      Allergic conditions
10.01.03      Allergic conditions NEC
10.01.03.006      Type I hypersensitivity
Description Hypersensitivity reactions which occur within minutes of exposure to challenging antigen due to the release of histamine which follows the antigen-antibody reaction and causes smooth muscle contraction and increased vascular permeability. [MeSH]
MedDRA Code 10045240
MeSH ID D006969
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE) Not Available
Synonym
Hypersensitivity type I | Hypersensitivity type I NOS | Immediate hypersensitivity | Immediate hypersensitivity reaction | Type I hypersensitivity | Hypersensitivity, Immediate | Hypersensitivities, Immediate | Immediate Hypersensitivities | Immediate Hypersensitivity | IgE-Mediated Hypersensitivity | Hypersensitivities, IgE-Mediated | Hypersensitivity, IgE-Mediated | IgE Mediated Hypersensitivity | IgE-Mediated Hypersensitivities | Hypersensitivity, Type I | Hypersensitivities, Type I | Type I Hypersensitivities | Atopic Hypersensitivity | Atopic Hypersensitivities | Hypersensitivities, Atopic | Hypersensitivity, Atopic | Type I Hypersensitivity
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D01981Salmeterol--
BADD_D02082Sufentanil0.000268%
BADD_D02084Sugammadex0.001239%
BADD_D02105Tacrolimus0.000891%
BADD_D02139Tegaserod maleate--
BADD_D02224Tiotropium bromide--
BADD_D02254Tramadol0.000022%
BADD_D02261Tranexamic acid0.003117%
BADD_D02272Triamcinolone acetonide0.000137%
BADD_D02321Ursodiol--
BADD_D02558Gadolinium cation (3+)-
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