Adverse Drug Reaction Classification System

ADR Ontology
ADR Term Vitamin B6 deficiency
ADR ID BADD_A04606
ADR Hierarchy
14      Metabolism and nutrition disorders
14.12      Vitamin related disorders
14.12.02      Water soluble vitamin deficiencies
14.12.02.005      Vitamin B6 deficiency
Description A nutritional condition produced by a deficiency of VITAMIN B 6 in the diet, characterized by dermatitis, glossitis, cheilosis, and stomatitis. Marked deficiency causes irritability, weakness, depression, dizziness, peripheral neuropathy, and seizures. In infants and children typical manifestations are diarrhea, anemia, and seizures. Deficiency can be caused by certain medications, such as isoniazid. | Deficiency of PYRIDOXINE, one of the VITAMIN B 6 compounds. Although pyridoxine and Vitamin B 6 are still frequently used as synonyms, especially by medical researchers, this practice is erroneous and sometimes misleading (EE Snell; Ann NY Acad Sci, vol 585 pg 1, 1990). [MeSH]
MedDRA Code 10047617
MeSH ID D026681
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE) Not Available
Synonym
Pyridoxine deficiency | Vitamin B6 deficiency | Vitamin B 6 Deficiency | Deficiency, Vitamin B6 | B6 Deficiencies, Vitamin | B6 Deficiency, Vitamin | Deficiencies, Vitamin B6 | Vitamin B6 Deficiencies | Vitamin Deficiency, B6 | B6 Vitamin Deficiencies | B6 Vitamin Deficiency | Deficiencies, B6 Vitamin | Deficiency, B6 Vitamin | Vitamin Deficiencies, B6 | Deficiency, Vitamin B 6 | Vitamin B6 Deficiency | Pyridoxine Deficiency | Deficiency, Pyridoxine
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D01204Isoniazid0.006949%
BADD_D01709Penicillamine--
BADD_D02223Tiopronin--
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