Adverse Drug Reaction Classification System

ADR Ontology
ADR Term Waldenstrom's macroglobulinaemia
ADR ID BADD_A04639
ADR Hierarchy
01      Blood and lymphatic system disorders
01.15      Lymphomas non-Hodgkin's B-cell
01.15.03      Waldenstrom's macroglobulinaemias
01.15.03.001      Waldenstrom's macroglobulinaemia
16      Neoplasms benign, malignant and unspecified (incl cysts and polyps)
16.28      Lymphomas non-Hodgkin's B-cell
16.28.03      Waldenstrom's macroglobulinaemias
16.28.03.001      Waldenstrom's macroglobulinaemia
Description A lymphoproliferative disorder characterized by pleomorphic B-LYMPHOCYTES including PLASMA CELLS, with increased levels of monoclonal serum IMMUNOGLOBULIN M. There is lymphoplasmacytic cells infiltration into bone marrow and often other tissues, also known as lymphoplasmacytic lymphoma. Clinical features include ANEMIA; HEMORRHAGES; and hyperviscosity. [MeSH]
MedDRA Code 10047801
MeSH ID D008258
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE) Not Available
Synonym
Macroglobulinaemia NOS | Macroglobulinemia | Von Waldenstrom macroglobulinaemia | Waldenstrom's macroglobulinaemia | Waldenstrom's macroglobulinaemia NOS | Von Waldenstrom macroglobulinemia | Waldenstrom's macroglobulinemia | Waldenstrom's macroglobulinemia NOS | Macroglobulinaemia | Primary macroglobulinemia | Primary macroglobulinaemia | Waldenstrom Macroglobulinemia | Macroglobulinemia, Waldenstrom | Lymphoma, Lymphoplasmacytoid | Lymphomas, Lymphoplasmacytoid | Lymphoplasmacytoid Lymphoma | Lymphoplasmacytoid Lymphomas | Waldenstrom's Macroglobulinemia | Macroglobulinemia, Waldenstrom's | Waldenstroms Macroglobulinemia | Waldenstrom's Macroglobulinaemia | Macroglobulinaemia, Waldenstrom's | Waldenstrom Macroglobulinaemia | Waldenstroms Macroglobulinaemia | Lymphoma, Lymphocytic, Plasmacytoid | Primary Macroglobulinemia | Macroglobulinemia, Primary | Familial Waldenstrom's Macroglobulinaemia | Familial Waldenstrom Macroglobulinaemia | Familial Waldenstroms Macroglobulinaemia | Macroglobulinaemia, Familial Waldenstrom's | Waldenstrom's Macroglobulinaemia, Familial
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00230Bendamustine0.000112%
BADD_D00284Bortezomib0.001455%
BADD_D00594Deferasirox0.002478%
BADD_D00680Dimethyl fumarate0.000400%
BADD_D01119Ibrutinib0.001119%
BADD_D01253Lenalidomide0.000723%
BADD_D01835Pregabalin0.000052%
BADD_D01953Rituximab--
BADD_D02345Venetoclax0.000168%
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