Adverse Drug Reaction Classification System

ADR Ontology
ADR Term Waxy flexibility
ADR ID BADD_A04647
ADR Hierarchy
19      Psychiatric disorders
19.11      Changes in physical activity
19.11.03      Stereotypies and automatisms
19.11.03.005      Waxy flexibility
Description A condition characterized by inactivity, decreased responsiveness to stimuli, and a tendency to maintain an immobile posture. The limbs tend to remain in whatever position they are placed (waxy flexibility). Catalepsy may be associated with PSYCHOTIC DISORDERS (e.g., SCHIZOPHRENIA, CATATONIC), nervous system drug toxicity, and other conditions. [MeSH]
MedDRA Code 10047853
MeSH ID D002375
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE) Not Available
Synonym
Catalepsy | Cerea flexibilitas | Waxy flexibility | Catalepsies | Anochlesia | Anochlesias | Cerea Flexibilitas | Flexibilitas, Cerea | Flexibility, Waxy | Flexibilities, Waxy | Waxy Flexibilities | Waxy Flexibility
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00499Clomipramine--
BADD_D00500Clomipramine hydrochloride--
BADD_D00511Clozapine0.002446%
BADD_D01318Lorazepam0.000031%
BADD_D01599Olanzapine0.000421%
BADD_D01951Risperidone0.000182%
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