Adverse Drug Reaction Classification System

ADR Ontology
ADR Term Joint range of motion decreased
ADR ID BADD_A04717
ADR Hierarchy
15      Musculoskeletal and connective tissue disorders
15.01      Joint disorders
15.01.02      Joint related signs and symptoms
15.01.02.006      Joint range of motion decreased
Description A disorder characterized by a decrease in joint flexibility of any joint. [CTCAE] A condition caused by degenerative arthritis (see OSTEOARTHRITIS) of the METATARSOPHALANGEAL JOINT of the great toe and characterized by pain and limited dorsiflexion, but relatively unrestricted plantar flexion. [MeSH]
MedDRA Code 10048706
MeSH ID D020859; D020857
ADR Severity Grade (FAERS) Not Available
ADR Severity Grade (CTCAE)
Synonym
Hallux rigidus | Joint range of motion decreased | Joint range of motion decreased cervical spine | Joint range of motion decreased lumbar spine | Hallux limitus | Hallux Rigidus | Rigidus, Hallux
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D01909Ramipril0.000140%
BADD_D01922Regorafenib0.000112%
BADD_D02028Sirolimus0.000134%
BADD_D02029Sitagliptin0.000053%
BADD_D02060Sotalol0.000281%
BADD_D02093Sulfasalazine0.001697%
BADD_D02236Tofacitinib0.132491%
BADD_D02329Valproic acid0.000100%
BADD_D02373Warfarin0.000042%
BADD_D02375Water--
BADD_D02407Upadacitinib0.000530%
BADD_D02412Octreotide--
BADD_D02436Atorvastatin--
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