Adverse Drug Reaction Classification System

ADR Ontology
ADR Term Lymphangioleiomyomatosis
ADR ID BADD_A04836
ADR Hierarchy
01      Blood and lymphatic system disorders
01.09      Spleen, lymphatic and reticuloendothelial system disorders
01.09.01      Lymphatic system disorders NEC
01.09.01.018      Lymphangioleiomyomatosis
22      Respiratory, thoracic and mediastinal disorders
22.01      Lower respiratory tract disorders (excl obstruction and infection)
22.01.02      Parenchymal lung disorders NEC
22.01.02.018      Lymphangioleiomyomatosis
24      Vascular disorders
24.09      Lymphatic vessel disorders
24.09.02      Lymphangiopathies
24.09.02.004      Lymphangioleiomyomatosis
Description A disease characterized by the progressive invasion of SMOOTH MUSCLE CELLS into the LYMPHATIC VESSELS, and the BLOOD VESSELS. The majority of the cases occur in the LUNGS of women of child-bearing age, eventually blocking the flow of air, blood, and lymph. The common symptom is shortness of breath (DYSPNEA). [MeSH]
MedDRA Code 10049459
MeSH ID D018192
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE) Not Available
Synonym
Lymphangioleiomyomatosis | Lymphangiomyomatosis | Lymphangioleiomyomatoses | Lymphangiomyomatoses
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00858Everolimus0.000229%
BADD_D01257Letrozole0.000527%
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