Adverse Drug Reaction Classification System

ADR Ontology
ADR Term Left ventricular dysfunction
ADR ID BADD_A04856
ADR Hierarchy
02      Cardiac disorders
02.04      Myocardial disorders
02.04.02      Myocardial disorders NEC
02.04.02.011      Left ventricular dysfunction
Description A condition in which the LEFT VENTRICLE of the heart was functionally impaired. This condition usually leads to HEART FAILURE; MYOCARDIAL INFARCTION; and other cardiovascular complications. Diagnosis is made by measuring the diminished ejection fraction and a depressed level of motility of the left ventricular wall. [MeSH]
MedDRA Code 10049694
MeSH ID D018487
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE)
Synonym
Post MI left ventricular dysfunction | Left ventricular dysfunction | Left ventricular systolic dysfunction | Left ventricular diastolic dysfunction | Ventricular Dysfunction, Left | Left Ventricular Dysfunction | Dysfunction, Left Ventricular | Dysfunctions, Left Ventricular | Left Ventricular Dysfunctions | Ventricular Dysfunctions, Left
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00653Diclofenac0.000038%
BADD_D00668Digoxin0.000105%
BADD_D00674Diltiazem0.000102%
BADD_D00699Docetaxel--
BADD_D00706Donepezil0.000070%
BADD_D00723Doxorubicin0.001847%
BADD_D00765Empagliflozin0.000091%
BADD_D00782Epinephrine0.000363%
BADD_D00809Escitalopram0.000019%
BADD_D00931Fluorouracil0.000643%
BADD_D00932Fluoxetine0.000030%
BADD_D00979Furosemide0.000028%
BADD_D01103Hydroxychloroquine0.002789%
BADD_D01119Ibrutinib0.000336%
BADD_D01136Imatinib0.000280%
BADD_D01217Itraconazole0.002672%
BADD_D01220Ivacaftor-
BADD_D01222Ixabepilone--
BADD_D01243Lamotrigine0.000055%
BADD_D01254Lenvatinib0.000414%
BADD_D01275Levofloxacin0.000084%
BADD_D01300Lisinopril0.000005%
BADD_D01303Lithium carbonate0.000803%
BADD_D01304Lithium cation0.000288%
BADD_D01318Lorazepam0.000031%
BADD_D01336Macitentan0.000301%
BADD_D01397Mesalamine0.000274%
BADD_D01401Metformin0.000030%
BADD_D01405Methadone0.000398%
BADD_D01431Methylphenidate0.000062%
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ADReCS-Target
ADR Term Drug Name Target