Adverse Drug Reaction Classification System

         

ADR Ontology
ADR Term Muscle tightness
ADR ID BADD_A04877
ADR Hierarchy
15      Musculoskeletal and connective tissue disorders
15.05      Muscle disorders
15.05.03      Muscle related signs and symptoms NEC
15.05.03.007      Muscle tightness
Description The state of activity or tension of a muscle beyond that related to its physical properties, that is, its active resistance to stretch. In skeletal muscle, tonus is dependent upon efferent innervation. (Stedman, 25th ed) [MeSH]
MedDRA Code 10049816
MeSH ID D009129
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE) Not Available
Synonym
Neck tightness | Perioral tension | Tightness in jaw | Tightness of jaw muscles | Muscle tightness | Tightness of back muscles | Muscle tension | Muscle Tonus | Tonus, Muscle | Muscle Tightness | Tightness, Muscle | Muscular Tension | Tension, Muscular | Muscle Tension | Tension, Muscle
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D01186Ioversol0.019206%
BADD_D01197Iron--
BADD_D01223Ixazomib0.000437%
BADD_D01243Lamotrigine0.000083%
BADD_D01253Lenalidomide0.015793%
BADD_D01254Lenvatinib0.000112%
BADD_D01275Levofloxacin0.000177%
BADD_D01281Levonorgestrel0.003735%
BADD_D01285Levothyroxine0.000028%
BADD_D01290Lifitegrast0.001563%
BADD_D01300Lisinopril0.000009%
BADD_D01318Lorazepam0.000083%
BADD_D01322Losartan0.000037%
BADD_D01405Methadone0.000265%
BADD_D01431Methylphenidate0.000193%
BADD_D01449Metronidazole0.000026%
BADD_D01533Naproxen--
BADD_D01535Naratriptan--
BADD_D01536Naratriptan hydrochloride--
BADD_D01564Nicotine0.000627%
BADD_D01623Oritavancin0.000107%
BADD_D01633Oxaliplatin0.000560%
BADD_D01656Paliperidone0.019260%
BADD_D01657Paliperidone palmitate--
BADD_D01668Pantoprazole--
BADD_D01679Paroxetine--
BADD_D01743Perphenazine--
BADD_D01774Pimozide--
BADD_D01798Pomalidomide0.004340%
BADD_D01818Pramipexole dihydrochloride--
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