Adverse Drug Reaction Classification System

         

ADR Ontology
ADR Term Lipase
ADR ID BADD_A04953
ADR Hierarchy
13      Investigations
13.05      Gastrointestinal investigations
13.05.01      Digestive enzymes
13.05.01.011      Lipase
Description An enzyme of the hydrolase class that catalyzes the reaction of triacylglycerol and water to yield diacylglycerol and a fatty acid anion. It is produced by glands on the tongue and by the pancreas and initiates the digestion of dietary fats. (From Dorland, 27th ed) EC 3.1.1.3. [MeSH]
MedDRA Code 10050659
MeSH ID D008049
ADR Severity Grade (FAERS) Not Available
ADR Severity Grade (CTCAE) Not Available
Synonym
Lipase | Triacylglycerol Lipase | Triolean Hydrolase | Hydrolase, Triolean | Triglyceridase | Triglyceride Lipase | Lipase, Triglyceride | Triacylglycerol Hydrolase | Hydrolase, Triacylglycerol | Tributyrinase | Acid Lipase A | Lipase A, Acid | Monoester Lipase | Lipase, Monoester | Acid Lipase I | Lipase I, Acid | Acid Lipase II | Lipase II, Acid | Exolipase | Acid Lipase | Lipase, Acid | Acid Lipase B | Lipase B, Acid
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00587Darunavir ethanolate--
BADD_D00704Dolutegravir sodium--
BADD_D00868Famciclovir--
BADD_D01242Lamivudine--
BADD_D01295Linezolid--
BADD_D01352Maraviroc--
BADD_D02383Zidovudine--
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