Adverse Drug Reaction Classification System

ADR Ontology
ADR Term Enterocutaneous fistula
ADR ID BADD_A05040
ADR Hierarchy
07      Gastrointestinal disorders
07.11      Gastrointestinal conditions NEC
07.11.05      Gastrointestinal fistulae
07.11.05.005      Enterocutaneous fistula
23      Skin and subcutaneous tissue disorders
23.07      Skin and subcutaneous tissue disorders NEC
23.07.04      Skin and subcutaneous conditions NEC
23.07.04.017      Enterocutaneous fistula
Description An abnormal anatomical passage between the INTESTINE, and another segment of the intestine or other organs. External intestinal fistula is connected to the SKIN (enterocutaneous fistula). Internal intestinal fistula can be connected to a number of organs, such as STOMACH (gastrocolic fistula), the BILIARY TRACT (cholecystoduodenal fistula), or the URINARY BLADDER of the URINARY TRACT (colovesical fistula). Risk factors include inflammatory processes, cancer, radiation treatment, and surgical misadventures (MEDICAL ERRORS). [MeSH]
MedDRA Code 10051425
MeSH ID D007412
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE) Not Available
Synonym
Enterocutaneous fistula | Colocutaneous fistula | Intestinal Fistula | Fistula, Intestinal | Colovesical Fistula | Fistula, Colovesical | Enterocutaneous Fistula | Fistula, Enterocutaneous | Cholecystoduodenal Fistula | Fistula, Cholecystoduodenal
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00195Azathioprine0.000783%
BADD_D00349Capecitabine0.000168%
BADD_D00474Cisplatin0.000112%
BADD_D01213Isotretinoin0.001544%
BADD_D01254Lenvatinib0.000168%
BADD_D01418Methotrexate--
BADD_D01449Metronidazole0.000039%
BADD_D01687Pazopanib0.000168%
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