Adverse Drug Reaction Classification System

         

ADR Ontology
ADR Term Neural tube defect
ADR ID BADD_A05080
ADR Hierarchy
03      Congenital, familial and genetic disorders
03.10      Neurological disorders congenital
03.10.02      Central nervous system disorders congenital NEC
03.10.02.003      Neural tube defect
17      Nervous system disorders
17.19      Congenital and peripartum neurological conditions
17.19.02      Congenital and hereditary neurological disorders NEC
17.19.02.002      Neural tube defect
Description Congenital malformations of the central nervous system and adjacent structures related to defective neural tube closure during the first trimester of pregnancy generally occurring between days 18-29 of gestation. Ectodermal and mesodermal malformations (mainly involving the skull and vertebrae) may occur as a result of defects of neural tube closure. (From Joynt, Clinical Neurology, 1992, Ch55, pp31-41) [MeSH]
MedDRA Code 10052046
MeSH ID D009436
ADR Severity Grade (FAERS) Not Available
ADR Severity Grade (CTCAE) Not Available
Synonym
Neural tube defect | Neural Tube Defects | Defect, Neural Tube | Defects, Neural Tube | Neural Tube Defect | Developmental Neural Tube Defects | Neural Tube Developmental Defects | Developmental Defects, Neural Tube | Craniorachischisis | Craniorachischises | Diastematomyelia | Diastematomyelias | Tethered Cord Syndrome | Tethered Cord Syndromes | Occult Spinal Dysraphism Sequence | Tethered Spinal Cord Syndrome | Occult Spinal Dysraphism | Dysraphism, Occult Spinal | Dysraphisms, Occult Spinal | Occult Spinal Dysraphisms | Spinal Dysraphism, Occult | Spinal Dysraphisms, Occult | Iniencephaly | Iniencephalies | Neurenteric Cyst | Cyst, Neurenteric | Cysts, Neurenteric | Neurenteric Cysts | Neuroenteric Cyst | Cyst, Neuroenteric | Cysts, Neuroenteric | Neuroenteric Cysts | Spinal Cord Myelodysplasia | Myelodysplasia, Spinal Cord | Myelodysplasias, Spinal Cord | Spinal Cord Myelodysplasias | Acrania | Acranias | Exencephaly | Exencephalies
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00497Clomiphene--
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