Adverse Drug Reaction Classification System

ADR Ontology
ADR Term Metabolic syndrome
ADR ID BADD_A05081
ADR Hierarchy
24      Vascular disorders
24.08      Vascular hypertensive disorders
24.08.02      Vascular hypertensive disorders NEC
24.08.02.014      Metabolic syndrome
05      Endocrine disorders
05.06      Glucose metabolism disorders (incl diabetes mellitus)
05.06.02      Hyperglycaemic conditions NEC
05.06.02.007      Metabolic syndrome
14      Metabolism and nutrition disorders
14.06      Glucose metabolism disorders (incl diabetes mellitus)
14.06.02      Hyperglycaemic conditions NEC
14.06.02.007      Metabolic syndrome
Description A cluster of symptoms that are risk factors for CARDIOVASCULAR DISEASES and TYPE 2 DIABETES MELLITUS. The major components of metabolic syndrome include ABDOMINAL OBESITY; atherogenic DYSLIPIDEMIA; HYPERTENSION; HYPERGLYCEMIA; INSULIN RESISTANCE; a proinflammatory state; and a prothrombotic (THROMBOSIS) state. [MeSH]
MedDRA Code 10052066
MeSH ID D024821
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE) Not Available
Synonym
Insulin resistance syndrome | Metabolic syndrome | Metabolic syndrome X | Dysmetabolic syndrome | Cardiometabolic syndrome | Metabolic Syndrome | Metabolic Syndromes | Syndrome, Metabolic | Syndromes, Metabolic | Metabolic Syndrome X | Insulin Resistance Syndrome X | Syndrome X, Metabolic | Syndrome X, Insulin Resistance | Metabolic X Syndrome | Syndrome, Metabolic X | X Syndrome, Metabolic | Dysmetabolic Syndrome X | Syndrome X, Dysmetabolic | Reaven Syndrome X | Syndrome X, Reaven | Metabolic Cardiovascular Syndrome | Cardiovascular Syndrome, Metabolic | Cardiovascular Syndromes, Metabolic | Syndrome, Metabolic Cardiovascular
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00066Alendronic acid0.000198%
BADD_D00165Aripiprazole0.000293%
BADD_D00364Carboplatin0.000112%
BADD_D00511Clozapine0.011617%
BADD_D00765Empagliflozin0.000200%
BADD_D00775Enzalutamide0.000334%
BADD_D00809Escitalopram0.000019%
BADD_D00898Finasteride0.000180%
BADD_D00932Fluoxetine0.000020%
BADD_D01213Isotretinoin0.000695%
BADD_D01318Lorazepam0.000077%
BADD_D01401Metformin0.000011%
BADD_D01563Nicotinate--
BADD_D01567Nilotinib0.000224%
BADD_D01599Olanzapine0.001937%
BADD_D01656Paliperidone0.009425%
BADD_D01835Pregabalin0.000052%
BADD_D01888Quetiapine0.000109%
BADD_D01909Ramipril0.000093%
BADD_D01951Risperidone0.002716%
BADD_D02047Sodium oxybate0.000590%
BADD_D02105Tacrolimus0.000297%
BADD_D02214Ticagrelor0.000598%
BADD_D02232Tobramycin--
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