Adverse Drug Reaction Classification System

ADR Ontology
ADR Term Major depression
ADR ID BADD_A05530
ADR Hierarchy
19      Psychiatric disorders
19.15      Depressed mood disorders and disturbances
19.15.01      Depressive disorders
19.15.01.003      Major depression
Description An affective disorder manifested by either a dysphoric mood or loss of interest or pleasure in usual activities. The mood disturbance is prominent and relatively persistent. [MeSH]
MedDRA Code 10057840
MeSH ID D003866; D003865
ADR Severity Grade (FAERS) Not Available
ADR Severity Grade (CTCAE) Not Available
Synonym
Depression endogenous | Depression psychotic | Depressive type psychosis | Endogenous depression | Involutional depression | Involutional melancholia | Major depressive disorder NOS | Major depressive disorder, recurrent episode | Major depressive disorder, recurrent episode, in full remission | Major depressive disorder, recurrent episode, in partial or unspecified remission | Major depressive disorder, recurrent episode, mild degree | Major depressive disorder, recurrent episode, moderate degree | Major depressive disorder, recurrent episode, severe degree, specified as with psychotic behavior | Major depressive disorder, recurrent episode, severe degree, specified as with psychotic behaviour | Major depressive disorder, recurrent episode, severe degree, without mention of psychotic behavior | Major depressive disorder, recurrent episode, unspecified degree | Major depressive disorder, single episode | Major depressive disorder, single episode in full remission | Major depressive disorder, single episode, in partial or unspecified remission | Major depressive disorder, single episode, mild degree | Major depressive disorder, single episode, moderate degree | Major depressive disorder, single episode, severe degree, specified as with psychotic behavior | Major depressive disorder, single episode, severe degree, without mention of psychotic behavior | Major depressive disorder, single episode, unspecified degree | Major depressive illness | Melancholia | Melancholic depression | Psychosis depressive | Psychotic depression | Major depressive disorder with melancholic features | Major depression | Major depressive disorder aggravated | Major depressive disorder | Clinical depression | Depressive Disorder | Depressive Disorders | Disorder, Depressive | Disorders, Depressive | Neurosis, Depressive | Depressive Neuroses | Depressive Neurosis | Neuroses, Depressive | Depression, Endogenous | Depressions, Endogenous | Endogenous Depression | Endogenous Depressions | Depressive Syndrome | Depressive Syndromes | Syndrome, Depressive | Syndromes, Depressive | Depression, Neurotic | Depressions, Neurotic | Neurotic Depression | Neurotic Depressions | Melancholias | Unipolar Depression | Depression, Unipolar | Depressions, Unipolar | Unipolar Depressions
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00947Fluticasone propionate--
BADD_D00948Fluvastatin0.000815%
BADD_D00950Fluvoxamine--
BADD_D00981Gabapentin0.000057%
BADD_D01020Glatiramer--
BADD_D01021Glatiramer acetate--
BADD_D01046Guanfacine--
BADD_D01132Idursulfase--
BADD_D01133Ifosfamide--
BADD_D01134Iloperidone--
BADD_D01213Isotretinoin0.004889%
BADD_D01228Ketamine0.000268%
BADD_D01257Letrozole0.000263%
BADD_D01260Leuprolide acetate0.002151%
BADD_D01265Levetiracetam0.000517%
BADD_D01281Levonorgestrel0.004728%
BADD_D01285Levothyroxine0.000032%
BADD_D01317Loratadine0.000032%
BADD_D01318Lorazepam0.000077%
BADD_D01330Lurasidone0.000721%
BADD_D01366Medroxyprogesterone acetate0.000178%
BADD_D01369Mefloquine--
BADD_D01431Methylphenidate0.000082%
BADD_D01433Methylprednisolone0.000064%
BADD_D01442Metoclopramide0.000196%
BADD_D01444Metolazone--
BADD_D01476Mirtazapine--
BADD_D01496Montelukast0.000278%
BADD_D01498Morphine0.000167%
BADD_D01567Nilotinib0.000168%
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