Adverse Drug Reaction Classification System

ADR Ontology
ADR Term Major depression
ADR ID BADD_A05530
ADR Hierarchy
19      Psychiatric disorders
19.15      Depressed mood disorders and disturbances
19.15.01      Depressive disorders
19.15.01.003      Major depression
Description An affective disorder manifested by either a dysphoric mood or loss of interest or pleasure in usual activities. The mood disturbance is prominent and relatively persistent. [MeSH]
MedDRA Code 10057840
MeSH ID D003866; D003865
ADR Severity Grade (FAERS) Not Available
ADR Severity Grade (CTCAE) Not Available
Synonym
Depression endogenous | Depression psychotic | Depressive type psychosis | Endogenous depression | Involutional depression | Involutional melancholia | Major depressive disorder NOS | Major depressive disorder, recurrent episode | Major depressive disorder, recurrent episode, in full remission | Major depressive disorder, recurrent episode, in partial or unspecified remission | Major depressive disorder, recurrent episode, mild degree | Major depressive disorder, recurrent episode, moderate degree | Major depressive disorder, recurrent episode, severe degree, specified as with psychotic behavior | Major depressive disorder, recurrent episode, severe degree, specified as with psychotic behaviour | Major depressive disorder, recurrent episode, severe degree, without mention of psychotic behavior | Major depressive disorder, recurrent episode, unspecified degree | Major depressive disorder, single episode | Major depressive disorder, single episode in full remission | Major depressive disorder, single episode, in partial or unspecified remission | Major depressive disorder, single episode, mild degree | Major depressive disorder, single episode, moderate degree | Major depressive disorder, single episode, severe degree, specified as with psychotic behavior | Major depressive disorder, single episode, severe degree, without mention of psychotic behavior | Major depressive disorder, single episode, unspecified degree | Major depressive illness | Melancholia | Melancholic depression | Psychosis depressive | Psychotic depression | Major depressive disorder with melancholic features | Major depression | Major depressive disorder aggravated | Major depressive disorder | Clinical depression | Depressive Disorder | Depressive Disorders | Disorder, Depressive | Disorders, Depressive | Neurosis, Depressive | Depressive Neuroses | Depressive Neurosis | Neuroses, Depressive | Depression, Endogenous | Depressions, Endogenous | Endogenous Depression | Endogenous Depressions | Depressive Syndrome | Depressive Syndromes | Syndrome, Depressive | Syndromes, Depressive | Depression, Neurotic | Depressions, Neurotic | Neurotic Depression | Neurotic Depressions | Melancholias | Unipolar Depression | Depression, Unipolar | Depressions, Unipolar | Unipolar Depressions
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D01645Oxycodone0.000166%
BADD_D01656Paliperidone0.006830%
BADD_D01668Pantoprazole0.000016%
BADD_D01679Paroxetine--
BADD_D01680Paroxetine hydrochloride--
BADD_D01681Paroxetine hydrochloride hemihydrate--
BADD_D01682Paroxetine impurity a--
BADD_D01683Paroxetine mesylate--
BADD_D01804Posaconazole--
BADD_D01817Pramipexole0.000319%
BADD_D01831Prednisolone0.000052%
BADD_D01834Prednisone0.000009%
BADD_D01835Pregabalin0.000415%
BADD_D01854Promethazine0.000058%
BADD_D01906Raltegravir potassium--
BADD_D01916Rasagiline mesylate--
BADD_D01933Ribavirin0.017801%
BADD_D01942Riluzole--
BADD_D01951Risperidone0.000182%
BADD_D01966Ropinirole--
BADD_D01981Salmeterol0.003263%
BADD_D02010Sertraline0.000064%
BADD_D02016Sibutramine--
BADD_D02026Simvastatin0.000007%
BADD_D02047Sodium oxybate0.002548%
BADD_D02066Spironolactone0.000037%
BADD_D02107Tafamidis0.000538%
BADD_D02247Topiramate0.000126%
BADD_D02254Tramadol0.000014%
BADD_D02337Varenicline0.001460%
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