Adverse Drug Reaction Classification System

ADR Ontology
ADR Term Trigeminal nerve disorder
ADR ID BADD_A05734
ADR Hierarchy
17      Nervous system disorders
17.04      Cranial nerve disorders (excl neoplasms)
17.04.08      Trigeminal disorders
17.04.08.004      Trigeminal nerve disorder
Description A disorder characterized by dysfunction of the trigeminal nerve (fifth cranial nerve). [CTCAE] Diseases of the trigeminal nerve or its nuclei, which are located in the pons and medulla. The nerve is composed of three divisions: ophthalmic, maxillary, and mandibular, which provide sensory innervation to structures of the face, sinuses, and portions of the cranial vault. The mandibular nerve also innervates muscles of mastication. Clinical features include loss of facial and intra-oral sensation and weakness of jaw closure. Common conditions affecting the nerve include brain stem ischemia, INFRATENTORIAL NEOPLASMS, and TRIGEMINAL NEURALGIA. [MeSH]
MedDRA Code 10060890
MeSH ID D020433
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE)
Synonym
Disorders of other cranial nerves | Other specified trigeminal nerve disorders | Trigeminal nerve disorder NOS | Trigeminal nerve disorder, unspecified | Trigeminal nerve disorders | Trigeminal nerve disorder | Trigeminal nerve dysfunction | Trigeminal Nerve Diseases | Trigeminal Nerve Disease | Trigeminal Neuropathy | Neuropathies, Trigeminal | Neuropathy, Trigeminal | Trigeminal Neuropathies | Trigeminal Nerve Disorders | Trigeminal Nerve Disorder | Cranial Nerve V Diseases | Fifth Cranial Nerve Diseases | Raeder Paratrigeminal Syndrome | Syndrome, Raeder Paratrigeminal | Trigeminal Neuropathy, Idiopathic | Idiopathic Trigeminal Neuropathies | Idiopathic Trigeminal Neuropathy | Neuropathies, Idiopathic Trigeminal | Neuropathy, Idiopathic Trigeminal | Trigeminal Neuropathies, Idiopathic
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00190Atropine sulfate--
BADD_D01831Prednisolone0.000035%
BADD_D02464Fingolimod0.000241%
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