Adverse Drug Reaction Classification System

         

ADR Ontology
ADR Term Optic neuropathy
ADR ID BADD_A05865
ADR Hierarchy
06      Eye disorders
06.02      Vision disorders
06.02.08      Visual pathway disorders
06.02.08.002      Optic neuropathy
17      Nervous system disorders
17.04      Cranial nerve disorders (excl neoplasms)
17.04.05      Optic nerve disorders NEC
17.04.05.005      Optic neuropathy
Description Conditions which produce injury or dysfunction of the second cranial or optic nerve, which is generally considered a component of the central nervous system. Damage to optic nerve fibers may occur at or near their origin in the retina, at the optic disk, or in the nerve, optic chiasm, optic tract, or lateral geniculate nuclei. Clinical manifestations may include decreased visual acuity and contrast sensitivity, impaired color vision, and an afferent pupillary defect. [MeSH]
MedDRA Code 10061323
MeSH ID D009901
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE) Not Available
Synonym
Nutritional optic neuropathy | Optic neuropathy NOS | Optic neuropathy | Progressive optic neuropathy | Optic Nerve Diseases | Optic Nerve Disease | Second Cranial Nerve Diseases | Neural-Optical Lesion | Lesion, Neural-Optical | Lesions, Neural-Optical | Neural Optical Lesion | Neural-Optical Lesions | Optic Neuropathy | Neuropathies, Optic | Neuropathy, Optic | Optic Neuropathies | Cranial Nerve II Diseases | Cranial Nerve II Disorder | Optic Disk Disorders | Disk Disorder, Optic | Disk Disorders, Optic | Optic Disk Disorder | Foster-Kennedy Syndrome | Foster Kennedy Syndrome | Syndrome, Foster-Kennedy
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00064Alemtuzumab--
BADD_D00108Aminohippurate sodium--
BADD_D00115Amiodarone0.001145%
BADD_D00284Bortezomib--
BADD_D00329Cabergoline0.004804%
BADD_D00356Carbamazepine0.000465%
BADD_D00480Clarithromycin0.000558%
BADD_D00535Crizotinib0.000112%
BADD_D00589Dasatinib0.000112%
BADD_D00623Dexamethasone0.000145%
BADD_D00712Dorzolamide0.000241%
BADD_D00749Efavirenz0.003670%
BADD_D00915Fludarabine phosphate--
BADD_D00931Fluorouracil0.000184%
BADD_D01103Hydroxychloroquine0.001859%
BADD_D01136Imatinib0.000224%
BADD_D01166Interferon alfa-2a--
BADD_D01201Isavuconazonium sulfate--
BADD_D01204Isoniazid0.004170%
BADD_D01275Levofloxacin0.000084%
BADD_D01285Levothyroxine0.000005%
BADD_D01295Linezolid0.063393%
BADD_D01378Memantine0.000121%
BADD_D01449Metronidazole0.000210%
BADD_D01620Oprelvekin--
BADD_D01653Paclitaxel0.000168%
BADD_D01834Prednisone0.000018%
BADD_D01888Quetiapine0.000055%
BADD_D01933Ribavirin0.007912%
BADD_D02018Sildenafil0.000161%
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