Adverse Drug Reaction Classification System

ADR Ontology
ADR Term Knee deformity
ADR ID BADD_A06051
ADR Hierarchy
15      Musculoskeletal and connective tissue disorders
15.10      Musculoskeletal and connective tissue deformities (incl intervertebral disc disorders)
15.10.03      Extremity deformities
15.10.03.002      Knee deformity
Description An inward slant of the thigh in which the knees are close together and the ankles far apart. Genu valgum can develop due to skeletal and joint dysplasias (e.g., OSTEOARTHRITIS; HURLER SYNDROME); and malnutrition (e.g., RICKETS; FLUORIDE POISONING). [MeSH]
MedDRA Code 10062061
MeSH ID D056304; D056305
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE) Not Available
Synonym
Genu recurvatum | Genu recurvatum (acquired) | Genu valgum | Genu valgum (acquired) | Genu valgum or varum (acquired) | Genu varum | Genu varum (acquired) | Hyperextension of knee | Knee deformity (acquired) | Knee deformity NOS | Knock-knee | Other acquired deformities of knee | Knee deformity | Patella alta | Bow legs | Patella baja | Patella infera | Fixed knee flexion deformity | Genu flexum | Genu Valgum | Genu Valgums | Knock Knee | Knees, Knock | Knock Knees | Genu Valga | Genu Valgas | Valga, Genu | Valgas, Genu
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00066Alendronic acid0.000330%
BADD_D00556Cysteamine--
BADD_D00557Cysteamine bitartrate--
BADD_D00596Deferoxamine0.001859%
BADD_D01213Isotretinoin0.000772%
BADD_D01285Levothyroxine0.000005%
BADD_D01418Methotrexate--
BADD_D01765Phenytoin0.000287%
BADD_D02165Teriflunomide0.001230%
BADD_D02192Thalidomide0.000241%
BADD_D02236Tofacitinib0.001881%
BADD_D02329Valproic acid0.000499%
BADD_D02392Zoledronic acid--
BADD_D02464Fingolimod0.000530%
BADD_D02504Lorlatinib0.000112%
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