Adverse Drug Reaction Classification System

ADR Ontology
ADR Term Metabolic encephalopathy
ADR ID BADD_A06071
ADR Hierarchy
14      Metabolism and nutrition disorders
14.11      Metabolism disorders NEC
14.11.01      Metabolic disorders NEC
14.11.01.013      Metabolic encephalopathy
17      Nervous system disorders
17.13      Encephalopathies
17.13.01      Encephalopathies toxic and metabolic
17.13.01.001      Metabolic encephalopathy
Description Acquired or inborn metabolic diseases that produce brain dysfunction or damage. These include primary (i.e., disorders intrinsic to the brain) and secondary (i.e., extracranial) metabolic conditions that adversely affect cerebral function. | Brain dysfunction or damage caused by acquired (i.e., non-inborn) metabolic disorders. Associated conditions include ENDOCRINE DISEASES; WATER-ELECTROLYTE IMBALANCE; KIDNEY DISEASES; LIVER DISEASES; anoxia (HYPOXIA, BRAIN); nutritional disorders (see NUTRITIONAL AND METABOLIC DISEASES); an encephalopathy associated with HEMODIALYSIS; and other disorders. (From Plum & Posner, Diagnosis of Stupor and Coma, 3rd ed, pp208-260) [MeSH]
MedDRA Code 10062190
MeSH ID D001928
ADR Severity Grade (FAERS) Not Available
ADR Severity Grade (CTCAE) Not Available
Synonym
Metabolic encephalopathy NOS | Metabolic encephalopathy | Brain Diseases, Metabolic | Brain Disease, Metabolic | Metabolic Brain Disease | Metabolic Disorders, Brain | Brain Metabolic Disorder | Brain Metabolic Disorders | Metabolic Disorder, Brain | Metabolic Encephalopathies | Metabolic Brain Syndromes | Brain Syndrome, Metabolic | Encephalopathies, Metabolic | Encephalopathy, Metabolic | Metabolic Encephalopathy | Metabolic Brain Syndrome | Metabolic Brain Diseases | Brain Disorders, Metabolic | Brain Disorder, Metabolic | Metabolic Brain Disorder | Metabolic Brain Disorders | Acquired Metabolic Diseases, Nervous System | Nervous System Acquired Metabolic Diseases | Metabolic Diseases, Acquired, Nervous System | Metabolic Disorder, Central Nervous System, Acquired | CNS Metabolic Disorders, Acquired | Metabolic Disorders, CNS, Acquired | Brain Diseases, Metabolic, Acquired | Acquired Metabolic Encephalopathies | Acquired Metabolic Encephalopathy | Encephalopathies, Acquired Metabolic | Encephalopathy, Acquired Metabolic | Metabolic Encephalopathies, Acquired | Metabolic Encephalopathy, Acquired | Brain Disorders, Metabolic, Acquired | Brain Syndrome, Metabolic, Acquired | Metabolic Brain Syndrome, Acquired | Metabolic Brain Syndromes, Acquired | Encephalopathy, Metabolic, Acquired | Acquired Metabolic Diseases, Brain | Metabolic Brain Diseases, Acquired | Central Nervous System Metabolic Disorders | Metabolic Disorders, Central Nervous System | CNS Metabolic Disorders | CNS Metabolic Disorder | Metabolic Disorder, CNS | Metabolic Disorders, CNS
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00023Acetaminophen--
BADD_D00039Acyclovir0.000071%
BADD_D00100Ambrisentan0.000120%
BADD_D00129Amoxicillin0.000007%
BADD_D00165Aripiprazole0.000159%
BADD_D00209Baclofen0.000766%
BADD_D00230Bendamustine0.000112%
BADD_D00274Bimatoprost0.000176%
BADD_D00285Bosentan0.000120%
BADD_D00344Canagliflozin0.000180%
BADD_D00356Carbamazepine0.000279%
BADD_D00386Cefepime0.000146%
BADD_D00405Ceftriaxone0.020946%
BADD_D00511Clozapine0.004891%
BADD_D00545Cyclobenzaprine0.000056%
BADD_D00563Dabigatran0.000612%
BADD_D00594Deferasirox0.002478%
BADD_D00648Diazepam0.000050%
BADD_D00802Ertapenem0.000073%
BADD_D00879Fentanyl0.000211%
BADD_D00979Furosemide0.000028%
BADD_D00981Gabapentin0.000026%
BADD_D01119Ibrutinib0.000168%
BADD_D01243Lamotrigine0.000166%
BADD_D01265Levetiracetam0.000159%
BADD_D01295Linezolid0.003293%
BADD_D01401Metformin0.000011%
BADD_D01549Nelarabine--
BADD_D01653Paclitaxel--
BADD_D01668Pantoprazole0.000049%
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