Adverse Drug Reaction Classification System

         

ADR Ontology
ADR Term Metastasis
ADR ID BADD_A06072
ADR Hierarchy
16      Neoplasms benign, malignant and unspecified (incl cysts and polyps)
16.22      Metastases
16.22.01      Metastases to unknown and unspecified sites
16.22.01.001      Metastasis
Description The transfer of a neoplasm from one organ or part of the body to another remote from the primary site. [MeSH]
MedDRA Code 10062194
MeSH ID D009362
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE) Not Available
Synonym
Metastases NOS | Secondary carcinoma | Secondary carcinoma (known primary) | Secondary malignant neoplasm of other specified site | Secondary malignant neoplasm of other specified site, not elsewhere classified | Secondary malignant neoplasm of other specified sites | Secondary malignant neoplasm of respiratory and digestive systems | Metastasis | Synchronous metastases | Metachronous metastasis | Neoplasm Metastasis | Metastases, Neoplasm | Neoplasm Metastases | Metastases | Metastasis, Neoplasm
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D01038Goserelin0.000334%
BADD_D01119Ibrutinib0.000224%
BADD_D01133Ifosfamide0.000224%
BADD_D01136Imatinib0.002350%
BADD_D01248Lapatinib0.000112%
BADD_D01257Letrozole0.001844%
BADD_D01260Leuprolide acetate0.004302%
BADD_D01378Memantine0.000181%
BADD_D01480Mitoxantrone--
BADD_D01567Nilotinib0.000168%
BADD_D01601Olaparib0.000728%
BADD_D01629Osimertinib0.000951%
BADD_D01633Oxaliplatin0.000280%
BADD_D01661Pamidronate disodium--
BADD_D01662Pamidronic acid--
BADD_D01687Pazopanib0.000783%
BADD_D01922Regorafenib0.000560%
BADD_D02026Simvastatin0.000018%
BADD_D02028Sirolimus0.000134%
BADD_D02029Sitagliptin0.000106%
BADD_D02058Sorafenib0.000783%
BADD_D02100Sunitinib--
BADD_D02111Tamoxifen--
BADD_D02150Temozolomide0.000470%
BADD_D02297Triptorelin--
BADD_D02331Valsartan0.000079%
BADD_D02344Vemurafenib0.000783%
BADD_D02345Venetoclax0.000112%
BADD_D02365Vismodegib0.000112%
BADD_D02375Water--
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